Document Detail

Swan-shaped bone fixation device made of Ni-Ti shape memory alloy for treating humeral fracture in rabbits.
MedLine Citation:
PMID:  12865234     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To establish the animal model for treating humeral fracture with swan-shaped bone fixation device made of Ni-Ti shape memory alloy. METHODS: Models of humeral fractures was established in 30 rabbits and on one side the fracture was fixed with the Ni-Ti shape memory alloy device (SMC side) and on the other with 4-hole dynamic compression plate (DCP side). Anteroposterior radiograph of both humeri were taken at the time points of 2, 4, 8, and 12 weeks respectively after operation. RESULTS: All the rabbits survived the experiment and their forelimbs bore obviously less weight than hindlimb. In SMC side, the humeral fracture healed without either osteoporosis or external callus. The fracture healing in DCP side gave rise to obvious external callus formation, and the healing process took significantly longer time than in SMC group. CONCLUSION: The humerus of rabbit is similar to human humerus in view of their anatomic morphology and biomechanical properties, therefore rabbit humeral fracture models can be ideal for exploring the mechanism of fracture healing induced by the alloy device.
Qing-lin Kang; Chun-cai Zhang; Tang-cheng Gao; Shuo-gui Xu; Ke Ren
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA     Volume:  23     ISSN:  1000-2588     ISO Abbreviation:  Di Yi Jun Yi Da Xue Xue Bao     Publication Date:  2003 Jul 
Date Detail:
Created Date:  2003-07-16     Completed Date:  2004-01-28     Revised Date:  2006-03-02    
Medline Journal Info:
Nlm Unique ID:  9426110     Medline TA:  Di Yi Jun Yi Da Xue Xue Bao     Country:  China    
Other Details:
Languages:  eng     Pagination:  728-30     Citation Subset:  IM    
Department of Orthopedics, Changhai Hospital, Second Military Medical University, Shanghai 200433, China.
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MeSH Terms
Fracture Fixation, Internal / adverse effects,  instrumentation*
Humeral Fractures / surgery*
Models, Animal
Orthopedic Fixation Devices*
Reg. No./Substance:
12035-60-8/titanium nickelide; 7440-02-0/Nickel; 7440-32-6/Titanium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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