Document Detail

Swallowing problems in rheumatoid arthritis.
MedLine Citation:
PMID:  1763639     Owner:  NLM     Status:  MEDLINE    
Twenty-nine female patients with definite or classical rheumatoid arthritis (RA) and 30 controls were investigated in order to evaluate oral symptoms, particularly xerostomia, and swallowing difficulties in RA by means of a questionnaire, physical examination, stimulated saliva secretion, labial salivary gland biopsy, esophageal manometry and laboratory blood tests. Xerostomia was reported by 6 patients (21%), compared with no-one in the control group. Four of these 6 patients had decreased stimulated saliva secretion, compared with 2 of the remaining 23 patients. Dysphagia was experienced by 8 patients (28%), compared with one control subject. Dysphagia was associated with disease severity. Esophageal manometry revealed a decrease of the amplitude of the peristaltic pressure complex in the proximal part of esophagus in the RA group, indicating dysfunction of the striated muscles. No correlation was found between dysphagia and esophageal manometry results.
A Geterud; B Bake; A Bjelle; R Jonsson; N Sandberg; H Ejnell
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Acta oto-laryngologica     Volume:  111     ISSN:  0001-6489     ISO Abbreviation:  Acta Otolaryngol.     Publication Date:  1991  
Date Detail:
Created Date:  1992-02-13     Completed Date:  1992-02-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370354     Medline TA:  Acta Otolaryngol     Country:  SWEDEN    
Other Details:
Languages:  eng     Pagination:  1153-61     Citation Subset:  IM    
Department of Otorhinolaryngology, University of Gothenburg, Sahlgren's Hospital, Sweden.
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MeSH Terms
Arthritis, Rheumatoid / complications*
Deglutition Disorders / diagnosis,  epidemiology,  etiology*
Esophagus / physiopathology
Middle Aged
Saliva / secretion
Sampling Studies
Xerostomia / diagnosis,  epidemiology,  etiology

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