| Sustained relief of dystonia following cessation of deep brain stimulation. | |
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MedLine Citation:
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PMID: 17674409 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We describe the unusual clinical course of a patient with cranial dystonia (i.e., Meige syndrome) and additional upper limb involvement, who developed sustained relief of motor symptoms following cessation of a prolonged course of bilateral pallidal deep brain stimulation (DBS). Early response to therapy proved titratable and reversible; however, the patient gained independence from DBS in the fifth postoperative year and has since been more than a year without treatment or exacerbation of motor symptoms. Among the potential explanations for these neurological benefits lies the intriguing possibility that DBS therapy may have the capacity to induce plastic change that lessens or obviates the need for further treatment in susceptible patients. |
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Authors:
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Matthew O Hebb; Paula Chiasson; Anthony E Lang; Robert M Brownstone; Ivar Mendez |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Movement disorders : official journal of the Movement Disorder Society Volume: 22 ISSN: 0885-3185 ISO Abbreviation: Mov. Disord. Publication Date: 2007 Oct |
Date Detail:
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Created Date: 2007-11-05 Completed Date: 2008-03-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8610688 Medline TA: Mov Disord Country: United States |
Other Details:
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Languages: eng Pagination: 1958-62 Citation Subset: IM |
Copyright Information:
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2007 Movement Disorder Society |
Affiliation:
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Division of Neurosurgery, Department of Surgery, Dalhousie University, Halifax, Nova Scotia, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Deep Brain Stimulation* Dominance, Cerebral / physiology Electrodes, Implanted Female Follow-Up Studies Globus Pallidus / physiopathology Humans Long-Term Care Magnetic Resonance Imaging Meige Syndrome / diagnosis, physiopathology, therapy* Middle Aged Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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