| Sustained monomorphic ventricular tachycardia in a patient with Brugada syndrome. | |
| | |
MedLine Citation:
|
PMID: 8844303 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We report a patient with Brugada syndrome who developed sustained monomorphic ventricular tachycardia (SMVT). The patient was a 29-year-old man who experienced recurrent episodes of palpitation and syncope after drinking alcohol. Electrocardiogram showed right bundle branch block and ST-segment elevation in precordial leads V1-3 without Q-Tc prolongation. Organic heart disease and coronary artery disease were excluded by noninvasive and invasive tests. Ventricular fibrillation was induced by the application of a single extra-stimulus to the right ventricular outflow tract. During isoproterenol infusion, SMVT of left bundle branch block morphology (240/min) was induced by the application of a single extrastimulus to the right ventricular apex. SMVT also developed spontaneously. Pace mapping disclosed that SMVT originated at the free wall of the right ventricular outflow tract. Head-up tilt test and an alcohol provocation test both induced similar SMVT that was associated with hypotension and near syncope. SMVT was not terminated by intravenous administration of lidocaine, procainamide or adenosine triphosphate (10 mg), but was terminated by propranolol. Thus, a beta-adrenoceptor-mediated mechanism appears to play an important role in SMVT in this patient. The site of origin of SMVT might be closely related to the lesion that causes ST-segment elevation. |
| | |
Authors:
|
M Shimada; T Miyazaki; S Miyoshi; K Soejima; S Hori; H Mitamura; S Ogawa |
Related Documents
:
|
3414923 - Complete heart block during anaesthesia in a patient with sarcoidosis. 1011513 - negative chrono- and inotropic effect of acetylcholine after its local administration t... 9111153 - Therapeutic implications of the epidemiology and timing of myocardial infarction and ot... |
Publication Detail:
|
Type: Case Reports; Journal Article |
Journal Detail:
|
Title: Japanese circulation journal Volume: 60 ISSN: 0047-1828 ISO Abbreviation: Jpn. Circ. J. Publication Date: 1996 Jun |
Date Detail:
|
Created Date: 1996-12-31 Completed Date: 1996-12-31 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7806868 Medline TA: Jpn Circ J Country: JAPAN |
Other Details:
|
Languages: eng Pagination: 364-70 Citation Subset: IM |
Affiliation:
|
Department of Internal Medicine, School of Medicine, Keio University, Tokyo, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Electrocardiography* Female Humans Male Syndrome Tachycardia, Ventricular / physiopathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Oxidative insult associated with hyperoxic cardiopulmonary bypass in the infantile heart and lung.
Next Document: A case of hypertrophic obstructive cardiomyopathy associated with autonomic nervous dysfunction.