| Sustained improvement with iloprost in a COPD patient with severe pulmonary hypertension. | |
| | |
MedLine Citation:
|
PMID: 19201716 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Pulmonary hypertension is an important complication of COPD. A small subset of patients with COPD have severe pulmonary hypertension (PH) that is out of proportion to the mild increase in pulmonary arterial pressure observed commonly. Severe PH associated with COPD is associated with increased morbidity and mortality. Treatment options in this group of patients are limited with no conclusive evidence of benefit when drugs approved for treatment of pulmonary arterial hypertension are used. We describe a patient with severe PH associated with COPD who improved clinically and hemodynamically when treated with inhaled iloprost. The improvement was sustained for 2 years. Severe PH in patients with COPD needs to be recognized and novel treatment approaches considered. |
| | |
Authors:
|
Matthew J Hegewald; C Gregory Elliott |
Related Documents
:
|
8989056 - Membrane diffusion and capillary blood volume in chronic thromboembolic pulmonary hyper... 10612386 - Pulmonary artery stenosis 5 years after single lung transplantation in primary pulmonar... 17892236 - Pulmonary hypertension: pathogenesis and management. 18091026 - Impaired systemic oxygen extraction at maximum exercise in pulmonary hypertension. 2388446 - Simultaneous coronary and abdominal aortic surgery--a report of two cases. 10348546 - Retrograde embolization during saphenous vein graft angioplasty. |
Publication Detail:
|
Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Chest Volume: 135 ISSN: 1931-3543 ISO Abbreviation: Chest Publication Date: 2009 Feb |
Date Detail:
|
Created Date: 2009-02-09 Completed Date: 2009-04-09 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0231335 Medline TA: Chest Country: United States |
Other Details:
|
Languages: eng Pagination: 536-7 Citation Subset: AIM; IM |
Affiliation:
|
Division of Pulmonary and Critical Care Medicine Intermountain Medical Center, University of Utah School of Medicine, Salt Lake City, UT 84157-7000, USA. matt.hegewald@imail.org |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Administration, Inhalation Aged Blood Gas Analysis Dose-Response Relationship, Drug Drug Administration Schedule Echocardiography, Transesophageal Follow-Up Studies Humans Hypertension, Pulmonary / drug therapy*, etiology, ultrasonography Iloprost / administration & dosage* Male Maximum Tolerated Dose Pulmonary Disease, Chronic Obstructive / complications*, diagnosis Respiratory Function Tests Risk Assessment Severity of Illness Index Treatment Outcome Vasodilator Agents / administration & dosage* |
| Chemical | |
Reg. No./Substance:
|
0/Vasodilator Agents; 78919-13-8/Iloprost |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Echocardiography performed by the pulmonary/critical care medicine physician.
Next Document: PHOX2B mutation-confirmed congenital central hypoventilation syndrome in a chinese family: presentat...