| Sustained efficacy and tolerability with vardenafil over 2 years of treatment in men with erectile dysfunction. | |
| | |
MedLine Citation:
|
PMID: 15117088 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This randomised, double-blind study assessed the long-term efficacy and tolerability of vardenafil 10 and 20 mg in men with erectile dysfunction (ED). A total of 566 men who completed an initial 12-month treatment period entered a 12-month extension. In these men, both doses of vardenafil produced improvement in scores for the 'erectile function' Domain of the International Index of Erectile Function, evident from week 4 and maintained through 2 years. Sexual Encounter Profile diary responses indicated that following treatment, penetration was achieved on 92-94% of attempts and erections that lasted long enough for successful intercourse were achieved on 87-89% of attempts. In response to the General Assessment Question, 90-92% of patients reported improved erections with vardenafil. Most treatment-emergent events were mild and transient with no cardiovascular safety concerns. These results support the long-term efficacy, reliability and tolerability of vardenafil 10 and 20 mg in men with ED. |
| | |
Authors:
|
C Stief; H Porst; I Sáenz De Tejada; E Ulbrich; M Beneke; |
Related Documents
:
|
19476738 - Zyflamend in men with high-grade prostatic intraepithelial neoplasia: results of a phas... 8411458 - Norfloxacin as prophylaxis against urethral strictures following transurethral resectio... 11275718 - Incidence and risk factors of bacteriuria after transurethral resection of the prostate. 19145438 - Impact of preoperative haemoglobin concentrations on the efficiency of ktp-laser vapori... 10853118 - Gamma knife radiosurgery for trigeminal neuralgia: experience at the barrow neurologica... 20509728 - Analysis of the subdural evacuating port system for the treatment of subacute and chron... |
Publication Detail:
|
Type: Clinical Trial; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: International journal of clinical practice Volume: 58 ISSN: 1368-5031 ISO Abbreviation: Int. J. Clin. Pract. Publication Date: 2004 Mar |
Date Detail:
|
Created Date: 2004-04-30 Completed Date: 2004-07-06 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9712381 Medline TA: Int J Clin Pract Country: England |
Other Details:
|
Languages: eng Pagination: 230-9 Citation Subset: IM |
Affiliation:
|
Department of Urology, Medizinische Hochschule, Hannover, Germany. stief.christian@mh-hannover.de |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Dose-Response Relationship, Drug Double-Blind Method Erectile Dysfunction / drug therapy* Humans Imidazoles / adverse effects, therapeutic use* Male Middle Aged Phosphodiesterase Inhibitors / adverse effects, therapeutic use* Piperazines / adverse effects, therapeutic use* Sulfones Treatment Outcome Triazines |
| Chemical | |
Reg. No./Substance:
|
0/Imidazoles; 0/Phosphodiesterase Inhibitors; 0/Piperazines; 0/Sulfones; 0/Triazines; 224785-90-4/vardenafil |
| Comments/Corrections | |
Comment In:
|
Int J Clin Pract. 2004 Mar;58(3):229
[PMID:
15117087
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Improved coupled-column liquid chromatographic method for the determination of glyphosate and aminom...
Next Document: Urinary beta-2 microglobulin in renal dysfunction associated with hypothyroidism.