Document Detail


Sustainable effect of Ayurvedic formulations in the treatment of nutritional anemia in adolescent students.
MedLine Citation:
PMID:  20180694     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: Anemia is a serious health problem in Indian school children. High prevalence of anemia has been reported in nonpregnant adolescent girls. An investigation was initiated to study the effect of two non-iron-containing Ayurvedic preparations-Sootshekhar Rasa plus Sitopaladi Churna-in improving nutritional anemia among adolescent students. DESIGN: This was a single-blinded, randomized, controlled study. SETTING: The study setting was Dehradun district, North India. SUBJECTS: The subjects comprised a total of 1646 boys and girls, aged 11-18 years, attending school in Dehradun district. INTERVENTION: As per World Health Organization guidelines, a total of 1322 adolescent anemic students were randomly divided into 5 groups. Students of group I (control) received starch. Group II, III, and IV students received Sootshekhar Rasa (SR) plus Sitopaladi Churna (SC) in various combinations, namely, SR 125 mg + SC 500 mg daily, SR 250 mg + SC 400 mg daily, and SR 250 mg + SC 400 mg weekly, respectively. Group V student were given iron and folic acid tablet. All the students received treatment for 90 days and were followed up for the next 180 days. OUTCOME MEASURE: The outcome measure was to evaluate the effect of Sootshekhar Rasa plus Sitopaladi Churna in improving nutritional anemia. RESULTS: The overall prevalence of anemia was found to be 81.3%. At baseline, the mean hemoglobin (Hb) was 97.4 +/- 13.2 g/L and ranged from 96.4 +/- 0.8 g/L to 98.3 +/- 0.8 g/L in various groups. At end of follow-up (day 270), a significant increase in Hb levels from baseline was observed in all treatment groups; however, the Hb gain (6.9 +/- 0.6 g/L) in group III and group V (3.64 +/- 0.56 g/L) differed significantly from the control group. A total of 155 students dropped out of the study due to various reasons not related to treatment. No adverse side-effect of Ayurvedic medication was noted in any student. CONCLUSIONS: We conclude that a daily dose of Sootshekhar Rasa (250 mg) plus Sitopaladi Churna (400 mg) can produce sustainable improvement of nutritional anemia in adolescent students.
Authors:
Vaidya Balendu Prakash; Shyam Prakash; Rajesh Sharma; Sanjoy K Pal
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of alternative and complementary medicine (New York, N.Y.)     Volume:  16     ISSN:  1557-7708     ISO Abbreviation:  J Altern Complement Med     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-02-25     Completed Date:  2010-06-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9508124     Medline TA:  J Altern Complement Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  205-11     Citation Subset:  IM    
Affiliation:
Vaidya Chandra Prakash Cancer Research Foundation, Dehradun, Uttarakhand, India.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Anemia / blood,  therapy*
Child
Drug Therapy, Combination
Female
Folic Acid / therapeutic use
Hemoglobins / metabolism*
Humans
Iron / therapeutic use
Male
Medicine, Ayurvedic*
Micronutrients / therapeutic use
Minerals / therapeutic use*
Phytotherapy*
Plant Extracts / therapeutic use*
Single-Blind Method
Chemical
Reg. No./Substance:
0/Hemoglobins; 0/Micronutrients; 0/Minerals; 0/Plant Extracts; 59-30-3/Folic Acid; 7439-89-6/Iron

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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