| Suspected coronary artery disease and myocardial infarction with normal coronary angiography: A heterogeneous but benign condition? | |
| | |
MedLine Citation:
|
PMID: 23453533 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
INTRODUCTION: Previous follow-up studies of patients with symptoms and/or non-invasive tests suggestive of ischemia or an acute coronary syndrome and a normal coronary angiogram have reported a good prognosis. OBJECTIVES: The aim of this study was to evaluate the clinical characteristics and outcome of a cohort of patients with suspected ischemic heart disease and normal coronary arteries. METHODS: A clinical follow-up was performed of 607 patients (mean age 62±11 years) with symptoms or non-invasive tests suggestive of ischemia (544) or myocardial infarction (63) and normal coronary angiography. The occurrence of major cardiac events or of readmission due to chest pain was recorded during a mean follow-up of 33.6±9.5 months after angiography. RESULTS: Patients with myocardial infarction were older (65.4±11.1 vs. 61.9±10.7, p=0.05), and the majority were women (68.3%). Hypertension was reported by 65.5% of patients, diabetes by 17.9%, dyslipidemia by 58.6%, smoking by 14% and family history of coronary artery disease in 11%. During follow-up no patient died from cardiovascular causes; three patients (0.5%) suffered myocardial infarction and 50 (8.3%) had recurrent chest pain leading to emergency admission. Patients with myocardial infarction had more events (20.6%) than those referred for angiography due to symptoms and/or positive non-invasive tests for ischemia (7.4%) (log-rank chi-square test: 13.6, p<0.0005). CONCLUSION: The incidence of risk factors was high. Our data suggest that patients with a normal angiogram had a good prognosis in spite of their baseline clinical presentation. A significant number of patients showed persistence of symptoms. |
| | |
Authors:
|
Nádia Moreira; Maria João Vidigal Ferreira; Francisco Soares; Beatriz Santos; Ana Miranda; Lino Gonçalves; Luís Providência |
Related Documents
:
|
23450513 - Sildenafil and diastolic dysfunction after acute myocardial infarction trial: rationale... 3664633 - Reporting, filing, and retrieval of coronary angiographic findings: a new personal comp... 487383 - Isoprenaline-induced myocardial infarction in spontaneously hypertensive rats. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2013-2-27 |
Journal Detail:
|
Title: Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology Volume: - ISSN: 0870-2551 ISO Abbreviation: Rev Port Cardiol Publication Date: 2013 Feb |
Date Detail:
|
Created Date: 2013-3-4 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8710716 Medline TA: Rev Port Cardiol Country: - |
Other Details:
|
Languages: ENG; POR Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2012 Sociedade Portuguesa de Cardiologia. Published by Elsevier España. All rights reserved. |
Affiliation:
|
Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal. Electronic address: nadia.moreira5@gmail.com. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Attitude toward epilepsy after media coverage of car accidents related to persons with epilepsy in J...
Next Document: Long-term effects of a cardiac rehabilitation program in the control of cardiovascular risk factors.