Document Detail

Suspect value of non-CSF viral cultures in the diagnosis of enteroviral CNS infection in young infants.
MedLine Citation:
PMID:  1327928     Owner:  NLM     Status:  MEDLINE    
Laboratory criteria used for presumptive diagnosis of enteroviral meningitis were evaluated as predictors of cerebrospinal fluid (CSF) infection. Records were retrospectively analysed of infants under four months of age admitted to hospital between 1977 and 1987 with viral CSF cultures: those with enteroviruses isolated from CSF (group 1) were compared with those with enteroviruses isolated only from non-CSF sites (group 2). Predictive value computations demonstrated that no single or combined non-CSF culture accurately predicted isolation of enteroviruses from the CSF. These results suggest that CSF viral culture is imperative in establishing the diagnosis of enteroviral meningitis in young infants.
G M Johnson; G A McAbee; E D Seaton; S M Lipson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Developmental medicine and child neurology     Volume:  34     ISSN:  0012-1622     ISO Abbreviation:  Dev Med Child Neurol     Publication Date:  1992 Oct 
Date Detail:
Created Date:  1992-11-18     Completed Date:  1992-11-18     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0006761     Medline TA:  Dev Med Child Neurol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  876-84     Citation Subset:  IM    
Department of Pediatrics, Nassau County Medical Center, East Meadow, NY 11554.
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MeSH Terms
Cerebrospinal Fluid / microbiology*
Diagnosis, Differential
Enterovirus / isolation & purification*
Enterovirus Infections / diagnosis*,  microbiology
Meningitis, Viral / diagnosis*,  microbiology
Neurologic Examination
Retrospective Studies
Virus Cultivation*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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