Document Detail

Susceptibility to Yersinia pestis in the northern grasshopper mouse (Onychomys leucogaster).
MedLine Citation:
PMID:  3373638     Owner:  NLM     Status:  MEDLINE    
The laboratory-born progeny from two geographically distant populations of northern grasshopper mice (Onychomys leucogaster) were challenged with Yersinia pestis to determine their relative susceptibilities to plague. One of the O. leucogaster populations was associated with a known epizootic focus of the disease and was found to be nearly 2,000 times more resistant to mortality than were members of another population from an area historically free of plague. The ecology and omnivorous behavior of O. leucogaster appears to promote strong selection for resistance to plague in areas where they are naturally exposed.
R E Thomas; A M Barnes; T J Quan; M L Beard; L G Carter; C E Hopla
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of wildlife diseases     Volume:  24     ISSN:  0090-3558     ISO Abbreviation:  J. Wildl. Dis.     Publication Date:  1988 Apr 
Date Detail:
Created Date:  1988-06-29     Completed Date:  1988-06-29     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0244160     Medline TA:  J Wildl Dis     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  327-33     Citation Subset:  IM    
Department of Zoology, University of Oklahoma, Norman 73019.
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MeSH Terms
Disease Susceptibility
Immunity, Innate
Muridae / classification,  immunology,  microbiology*
Plague / epidemiology,  mortality,  veterinary*
Rodent Diseases / microbiology*
Species Specificity

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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