| Susceptibility loci for complex regional pain syndrome. | |
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MedLine Citation:
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PMID: 12749963 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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An association between HLA-DR13 and patients with complex regional pain syndrome (CRPS) who progressed towards multifocal or generalized tonic dystonia was recently reported. We now report on a new locus, centromeric in HLA-class I, which was significantly associated with a spontaneous development of CRPS, suggesting an interaction between trauma severity and genetic factors conferring CRPS susceptibility. Additionally, an association with the D6S1014 locus was found, supporting the previous finding of an association with HLA-DR13. |
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Authors:
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Willem-Johan T van de Beek; Bart O Roep; Arno R van der Slik; Marius J Giphart; Bob J van Hilten |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Pain Volume: 103 ISSN: 0304-3959 ISO Abbreviation: Pain Publication Date: 2003 May |
Date Detail:
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Created Date: 2003-05-16 Completed Date: 2003-07-21 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7508686 Medline TA: Pain Country: Netherlands |
Other Details:
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Languages: eng Pagination: 93-7 Citation Subset: IM |
Affiliation:
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Department of Neurology, Leiden University Medical Center, P.O. Box 9600, 2300 RC, Leiden, The Netherlands. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Chromosome Mapping Chromosomes Complex Regional Pain Syndromes / genetics* Female Gene Frequency Genes, MHC Class I* Genetic Predisposition to Disease* HLA-DR Antigens / genetics Humans Linkage (Genetics) Microsatellite Repeats / genetics Middle Aged Nucleic Acid Amplification Techniques / methods Wounds and Injuries / genetics |
| Chemical | |
Reg. No./Substance:
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0/HLA-DR Antigens; 0/HLA-DR13 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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