Document Detail

Susceptibility of human enterotoxigenic Escherichia coli isolates to growth inhibition by porcine intestinal epithelial cells.
MedLine Citation:
PMID:  17590226     Owner:  NLM     Status:  MEDLINE    
Growth of human, but not porcine enterotoxigenic Escherichia coli (ETEC) isolates is inhibited during incubation with porcine intestinal epithelial cells and by a constitutively produced factor(s) present in unstimulated cell supernatants. The inhibitory factor(s) is heat stable, not produced by serum-starved cells, and is present in a diverse number of cultured epithelial cell lines of animal, but not of human origin. Susceptibility to porcine intestinal epithelial cells appears to be restricted to ETEC and not E. coli O157:H7 disease isolates.
Eric A Brown; Radhey S Kaushik; Philip R Hardwidge
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Publication Detail:
Type:  Journal Article     Date:  2007-06-21
Journal Detail:
Title:  FEMS microbiology letters     Volume:  274     ISSN:  0378-1097     ISO Abbreviation:  FEMS Microbiol. Lett.     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-07-31     Completed Date:  2007-09-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7705721     Medline TA:  FEMS Microbiol Lett     Country:  England    
Other Details:
Languages:  eng     Pagination:  95-101     Citation Subset:  IM    
Center for Infectious Disease Research and Vaccinology, South Dakota State University, Brookings, SD 57007, USA.
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MeSH Terms
Bacterial Adhesion
Biological Factors / pharmacology*
Cell Line
Escherichia coli / drug effects,  growth & development*,  isolation & purification
Intestinal Mucosa / cytology,  microbiology*
Microbial Sensitivity Tests
Swine / microbiology*
Reg. No./Substance:
0/Biological Factors

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