| Susceptibility contrast and arterial spin labeled perfusion MRI in cerebrovascular disease. | |
| | |
MedLine Citation:
|
PMID: 12593127 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
PURPOSE: To directly compare dynamic susceptibility contrast (DSC) and continuous arterial spin labeled (CASL) magnetic resonance (MR) perfusion techniques in patients with known cerebrovascular disease, with the goals of identifying possible pitfalls in interpretation and determining potential for a complementary role in this setting. METHODS: DSC and CASL MR perfusion studies were performed and compared in 11 patients with acute and/or chronic cerebrovascular disease. Using an automated segmentation technique, Pearson correlation coefficients were generated for CASL perfusion measurements compared to DSC perfusion maps (time-to-peak [TTP], relative cerebral blood volume [rCBV], cerebral blood flow [rCBF], and mean transit time [MTT]) by hemisphere and vascular territory. RESULTS: TTP maps obtained using DSC perfusion MR correlated best both subjectively and objectively with CASL perfusion MR measurements when all patients studied were considered. If patients with a major transit delay were excluded, DSC rCBF correlated best with CASL CBF measurements. CONCLUSION: There may be a complementary role for CASL and DSC perfusion MR methods in cerebrovascular disease, especially in the setting of a marked transit delay. |
| | |
Authors:
|
Ronald L Wolf; David C Alsop; Michael L McGarvey; Joseph A Maldjian; Jiongjiong Wang; John A Detre |
Related Documents
:
|
21732937 - Mri-negative epilepsy: protocols to optimize lesion detection. 16801657 - Diagnostic performance of spectroscopic and perfusion mri for distinction of brain tumors. 2501987 - Cerebral infarction: diagnosis and assessment of prognosis by using 123imp-spect and ct. 11442967 - Carotid endarterectomy and intraoperative emboli detection: correlation of clinical, tr... 9744637 - Brainstem lesion in aicardi-goutières syndrome. 22592047 - Role of positron emission tomography-computed tomography in the management of anal cancer. |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Journal of neuroimaging : official journal of the American Society of Neuroimaging Volume: 13 ISSN: 1051-2284 ISO Abbreviation: J Neuroimaging Publication Date: 2003 Jan |
Date Detail:
|
Created Date: 2003-02-20 Completed Date: 2003-03-21 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9102705 Medline TA: J Neuroimaging Country: United States |
Other Details:
|
Languages: eng Pagination: 17-27 Citation Subset: IM |
Affiliation:
|
Department of Radiology, University of Pennsylvania Medical Center, 3400 Spruce Street, Philadelphia, PA 19104, USA. wolf@rad.upenn.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acute Disease Adult Aged Brain / blood supply* Cerebral Infarction / diagnosis*, physiopathology Female Humans Ischemic Attack, Transient / diagnosis*, physiopathology Magnetic Resonance Imaging / methods* Male Middle Aged Regional Blood Flow Spin Labels |
| Chemical | |
Reg. No./Substance:
|
0/Spin Labels |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Approach to imaging the patient with neck pain.
Next Document: Residual flow signals predict complete recanalization in stroke patients treated with TPA.