Document Detail

Susceptibility of C5b-9(m) to postmortem changes.
MedLine Citation:
PMID:  7524628     Owner:  NLM     Status:  MEDLINE    
C5b-9(m) is a specific and sensitive marker for myocardial cell necrosis. The diagnostic value of this marker would be considerably limited in forensic practice if its immuno-histochemical demonstration were hampered by putrefaction or autolysis. We could demonstrate C5b-9(m) immunohistochemically in necrotic myocardium due to infarction up to the 11th day of experimentally induced putrefaction and autolysis, when reliable demonstration of myocardial infarction with hematoxylin-eosin was no longer possible. Under the experimental conditions of this study, no false positive immunohistochemical staining occurred.
H Thomsen; H Held
Related Documents :
25444758 - Histone deacetylases as therapeutic targets - from cancer to cardiac disease.
25215628 - Ventricular and atrial mechanics and their interaction in patients with congenital scol...
25276778 - Cardioprotection: a review of current practice in global ischemia and future translatio...
25267798 - Increased reactive oxygen species, metabolic maladaptation, and autophagy contribute to...
17322368 - Macrophage depletion impairs wound healing and increases left ventricular remodeling af...
20129298 - Atrial electrophysiological and structural remodeling in high-risk patients with brugad...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  International journal of legal medicine     Volume:  106     ISSN:  0937-9827     ISO Abbreviation:  Int. J. Legal Med.     Publication Date:  1994  
Date Detail:
Created Date:  1994-12-20     Completed Date:  1994-12-20     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9101456     Medline TA:  Int J Legal Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  291-3     Citation Subset:  IM    
Institute of Forensic Medicine, Christian-Albrechts University, Kiel, Germany.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Bias (Epidemiology)
Biological Markers / analysis
Complement Membrane Attack Complex / analysis*
Eosine Yellowish-(YS)
Evaluation Studies as Topic
False Positive Reactions
Forensic Medicine / methods
Immunohistochemistry / methods*
Myocardial Infarction / pathology*
Postmortem Changes*
Reproducibility of Results
Sensitivity and Specificity
Time Factors
Reg. No./Substance:
0/Biological Markers; 0/Complement Membrane Attack Complex; 17372-87-1/Eosine Yellowish-(YS); 517-28-2/Hematoxylin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Expression pattern of parathyroid hormone/parathyroid hormone related peptide receptor mRNA in mouse...
Next Document:  The value of the Lugol's iodine staining technique for the identification of vaginal epithelial cell...