| Susceptibility of C5b-9(m) to postmortem changes. | |
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MedLine Citation:
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PMID: 7524628 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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C5b-9(m) is a specific and sensitive marker for myocardial cell necrosis. The diagnostic value of this marker would be considerably limited in forensic practice if its immuno-histochemical demonstration were hampered by putrefaction or autolysis. We could demonstrate C5b-9(m) immunohistochemically in necrotic myocardium due to infarction up to the 11th day of experimentally induced putrefaction and autolysis, when reliable demonstration of myocardial infarction with hematoxylin-eosin was no longer possible. Under the experimental conditions of this study, no false positive immunohistochemical staining occurred. |
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Authors:
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H Thomsen; H Held |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: International journal of legal medicine Volume: 106 ISSN: 0937-9827 ISO Abbreviation: Int. J. Legal Med. Publication Date: 1994 |
Date Detail:
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Created Date: 1994-12-20 Completed Date: 1994-12-20 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 9101456 Medline TA: Int J Legal Med Country: GERMANY |
Other Details:
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Languages: eng Pagination: 291-3 Citation Subset: IM |
Affiliation:
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Institute of Forensic Medicine, Christian-Albrechts University, Kiel, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Bias (Epidemiology) Biological Markers / analysis Complement Membrane Attack Complex / analysis* Eosine Yellowish-(YS) Evaluation Studies as Topic False Positive Reactions Forensic Medicine / methods Hematoxylin Humans Immunohistochemistry / methods* Myocardial Infarction / pathology* Necrosis Postmortem Changes* Reproducibility of Results Sensitivity and Specificity Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Complement Membrane Attack Complex; 17372-87-1/Eosine Yellowish-(YS); 517-28-2/Hematoxylin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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