Document Detail

Survival prospects of extremely preterm infants: a 10-year experience in a single perinatal center.
MedLine Citation:
PMID:  1575836     Owner:  NLM     Status:  MEDLINE    
During a 10-year period, 1977 to 1986, 233 (53%) of 442 inborn live births between 23 and 28 weeks' gestation survived; their 1-year survival rate was 7% at 23 weeks, 30% at 24 weeks, 31% at 25 weeks, 55% at 26 weeks, 67% at 27 weeks, and 71% at 28 weeks. No significant change in survival rate was observed over the years. Twelve percent of pregnancies and 20% of infants were multiple gestations. Singleton births had significantly higher survival rates compared with multiple births (58% versus 41%). The obstetric intervention rate, as measured by the frequency of cesarean section, increased significantly over the years: from 15% in 1977-1978 to 33% in 1985-1986. The neonatal intervention rate, as measured by the frequency of live births offered neonatal intensive care, remained unchanged. Ten percent were not treated: 4% had major malformations and 6% were considered "nonviable." Active perinatal management, which assumed fetal-neonatal viability, accounted for better survival rates compared with centers with a more passive management policy. Information on survival based on gestational cohorts plays an important role in helping obstetricians, neonatologists, and parents make appropriate management decisions.
V Y Yu; J M Gomez; V Shah; P I McCloud
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of perinatology     Volume:  9     ISSN:  0735-1631     ISO Abbreviation:  Am J Perinatol     Publication Date:  1992 May 
Date Detail:
Created Date:  1992-06-11     Completed Date:  1992-06-11     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8405212     Medline TA:  Am J Perinatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  164-9     Citation Subset:  IM    
Department of Paediatrics, Monash University, Monash Medical Centre, Clayton, Victoria, Australia.
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MeSH Terms
Cesarean Section / statistics & numerical data
Cohort Studies
Congenital Abnormalities / mortality*
Infant Mortality / trends
Infant, Newborn
Infant, Premature, Diseases / mortality*
Intensive Care, Neonatal / statistics & numerical data
Pregnancy, Multiple
Regression Analysis
Survival Rate
Victoria / epidemiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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