Document Detail


Survival prediction of terminally ill cancer patients by clinical symptoms: development of a simple indicator.
MedLine Citation:
PMID:  10225699     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Although accurate prediction of survival is essential for palliative care, no clinical tools have been established. METHODS: Performance status and clinical symptoms were prospectively assessed on two independent series of terminally ill cancer patients (training set, n = 150; testing set, n = 95). On the training set, the cases were divided into two groups with or without a risk factor for shorter than 3 and 6 weeks survival, according to the way the classification achieved acceptable predictive value. The validity of this classification for survival prediction was examined on the test samples. RESULTS: The cases with performance status 10 or 20, dyspnea at rest or delirium were classified in the group with a predicted survival of shorter than 3 weeks. The cases with performance status 10 or 20, edema, dyspnea at rest or delirium were classified in the group with a predicted survival of shorter than 6 weeks. On the training set, this classification predicted 3 and 6 weeks survival with sensitivity 75 and 76% and specificity 84 and 78%, respectively. On the test populations, whether patients survived for 3 and 6 weeks or not was predicted with sensitivity 85 and 79% and specificity 84 and 72%, respectively. CONCLUSION: Whether or not patients live for 3 and 6 weeks can be acceptably predicted by this simple classification.
Authors:
T Morita; J Tsunoda; S Inoue; S Chihara
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Japanese journal of clinical oncology     Volume:  29     ISSN:  0368-2811     ISO Abbreviation:  Jpn. J. Clin. Oncol.     Publication Date:  1999 Mar 
Date Detail:
Created Date:  1999-05-12     Completed Date:  1999-05-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0313225     Medline TA:  Jpn J Clin Oncol     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  156-9     Citation Subset:  IM    
Affiliation:
Seirei Hospice, Seirei Mikatabara Hospital, Hamamatsu, Shizuoka, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aged
Delirium / classification
Dyspnea / classification
Female
Forecasting
Humans
Karnofsky Performance Status
Life Expectancy*
Male
Middle Aged
Neoplasms / mortality*,  therapy
Palliative Care
Predictive Value of Tests
Prognosis
Risk Assessment
Terminally Ill*

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