| Survival of patients with breast cancer diagnosed in the United Kingdom trial of early detection of breast cancer. United Kingdom Trial of Early Detection of Breast Cancer Group. | |
| | |
MedLine Citation:
|
PMID: 8790516 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: To examine the survival of patients with breast cancer diagnosed in different centres and by different methods in the United Kingdom trial of early detection of breast cancer, in order to investigate the contribution of different factors to the previously observed reductions in breast cancer mortality. SETTING: A non-randomised trial of the early detection of breast cancer, in which women aged 45-64 in two districts were offered annual screening for seven years, women in a further two districts were offered education about breast self examination (BSE), and those in four districts formed a comparison group. METHODS: Patients with breast cancer are classified according to the type of centre, method of detection, and attendance for BSE education. Univariate and multivariate survival analyses are carried out, including tumour size, dissemination status, and use of adjuvant treatment as additional variables. RESULTS: In the univariate analysis, patients with breast cancer who are non-attenders for screening have a significantly worse prognosis than those in the comparison centres. Patients whose cancer is detected by mammography have the best survival rate. The inclusion of size and dissemination status in the multivariate analysis explains only about one third of the improved prognosis in these cases. There is a significant difference between prognosis in the two BSE centres. CONCLUSIONS: The use of prognostic factors as recorded in this trial to predict breast cancer mortality may be inadequate. |
| | |
Authors:
|
S M Moss; R Ellman; D Coleman; J Chamberlain |
Related Documents
:
|
10127176 - Age differences in the breast cancer management of rural women. 16643266 - Women's perceptions of events impeding or facilitating the detection, investigation and... 12492466 - Living with breast cancer - a challenge to expansive and creative forces. 19827866 - Effects of reproductive factors on risk of breast cancer: a literature review. 18630506 - Inhibition of steroid sulphatase activity via the percutaneous route: a new option for ... 16925756 - Efficacy of primary hormone therapy for localized or locally advanced prostate cancer: ... |
Publication Detail:
|
Type: Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article |
Journal Detail:
|
Title: Journal of medical screening Volume: 1 ISSN: 0969-1413 ISO Abbreviation: J Med Screen Publication Date: 1994 Jul |
Date Detail:
|
Created Date: 1996-10-18 Completed Date: 1996-10-18 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9433359 Medline TA: J Med Screen Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 193-8 Citation Subset: IM |
Affiliation:
|
Trial Co-ordinating Centre, Institute of Cancer Research, Sutton, Surrey, United Kingdom. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Analysis of Variance Breast Neoplasms / diagnosis, mortality, pathology, prevention & control* Breast Self-Examination Female Great Britain / epidemiology Humans Mammography* Mass Screening* Middle Aged Multivariate Analysis Neoplasm Staging Patient Education as Topic Survival Rate Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Assessment of lesions detected at mammographic screening: performance at first or repeat screening i...
Next Document: Improving breast screening uptake: persuading initial non-attenders to attend.