| Survival and major neonatal complications in infants born between 22 0/7 and 24 6/7 weeks of gestation (1999-2003). | |
| | |
MedLine Citation:
|
PMID: 16678782 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: This study was undertaken to compare survival and morbidity until discharge in infants born after 22-23 versus 24 weeks' gestational age (GA). STUDY DESIGN: Cohort study of all infants 25 weeks or less, born in 3 tertiary perinatal centers (1999-2003). RESULTS: Of a total of 336 infants, 133 (40%) died before or immediately after birth without the provision of life support, 203 (60%) received active neonatal treatment. Infants with life support (n = 82 at 22 to 23 weeks, n = 121 at 24 weeks) differed with respect to antenatal steroid prophylaxis (44% vs 62%) and cesarean section rate (51% vs 71%). Survival was 67% compared with 82% (P = .016). The incidence of intraventricular hemorrhage III or greater or periventricular leukomalacia (15/15%), severe retinopathy of prematurity (18/15%), and chronic lung disease (40/47%) was similar in both GA groups. CONCLUSIONS: The provision of life support for extremely preterm infants increases their chance of survival without more neonatal morbidity. |
| | |
Authors:
|
Susanne Herber-Jonat; Andreas Schulze; Angela Kribs; Bernhard Roth; Wolfgang Lindner; Frank Pohlandt |
Publication Detail:
|
Type: Comparative Study; Journal Article; Multicenter Study Date: 2006-05-05 |
Journal Detail:
|
Title: American journal of obstetrics and gynecology Volume: 195 ISSN: 1097-6868 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 2006 Jul |
Date Detail:
|
Created Date: 2006-07-03 Completed Date: 2006-07-24 Revised Date: 2007-05-17 |
Medline Journal Info:
|
Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: United States |
Other Details:
|
Languages: eng Pagination: 16-22 Citation Subset: AIM; IM |
Affiliation:
|
Department of Obstetrics and Gynecology, Divisison of Neonatology, Klinikum Grosshadern, University of Munich, Munich, Germany. susanne.herber-jonat@med.uni-muenchen.de |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Cause of Death Cohort Studies Female Gestational Age* Humans Infant, Newborn Infant, Premature Infant, Premature, Diseases / epidemiology*, mortality Life Support Care* Logistic Models Male Morbidity Respiration, Artificial / statistics & numerical data Survival Analysis |
| Comments/Corrections | |
Comment In:
|
Am J Obstet Gynecol. 2007 May;196(5):e60; author reply e60-1
[PMID:
17466688
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Placental transfer of lopinavir/ritonavir in the ex vivo human cotyledon perfusion model.
Next Document: Epidermal growth factor synergistically enhances interleukin-8 production in human gingival fibrobla...