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Survival and biofilm formation of Listeria monocytogenes in simulated vaginal fluid: influence of pH and strain origin.
MedLine Citation:
PMID:  21569122     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Listeria monocytogenes, the responsible agent for listeriosis, can be transmitted from mother to fetus/neonates by vertical transmission, transplacentally or during passage through the birth canal. The purpose of this study was to investigate the survival and biofilm formation of L. monocytogenes (isolated from clinical cases or from food) in simulated vaginal fluid at different pH values (4.2, 5.5 and 6.5). Results demonstrated that this pathogen is inhibited by the normal vaginal pH but may proliferate when it increases. Clinical strains were significantly more resistant to pH 4.2 than food isolates. L. monocytogenes survived and even grew at the higher pHs investigated, suggesting that fetus/neonates from women having increased vaginal pH values during pregnancy, may be at higher risk of listeriosis. All isolates tested were producers of biofilm at different pH values, however L. monocytogenes produced higher quantities of biofilm in nutrient-rich medium. No significant differences in biofilm production were detected between food and clinical isolates. As L. monocytogenes are biofilm producers, this increases the probability of occurrence of neonatal infection.
Authors:
Sandra F Borges; Joana G L Silva; Paula C M Teixeira
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-5-13
Journal Detail:
Title:  FEMS immunology and medical microbiology     Volume:  -     ISSN:  1574-695X     ISO Abbreviation:  -     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-5-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9315554     Medline TA:  FEMS Immunol Med Microbiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved.
Affiliation:
CBQF/Escola Superior de Biotecnologia, Universidade Católica Portuguesa; Rua Dr. António Bernardino de Almeida, 4200- 072 Porto, Portugal.
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