| Survival after transfusion in the Netherlands. | |
| | |
MedLine Citation:
|
PMID: 20726957 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
BACKGROUND: Cost-effectiveness analyses of blood safety interventions require estimates of the life expectancy after blood product transfusion. These are best derived from survival after blood transfusion, per age group and blood component type. STUDY DESIGN AND METHODS: In the PROTON (PROfiles of TransfusiON recipients) study transfusion recipient data was collected from a hospital sample covering 28% of the total blood use between 1996 and 2006 in the Netherlands. The dataset includes date of transfusion, blood component type transfused and recipient identification details. PROTON data were individually matched to mortality data of the Netherlands. Survival after first transfusion and after any transfusion was calculated, per blood component type and age group. PROTON mortality rates were compared to mortality rates in the general population. The results were used to estimate survival beyond the study period and to estimate life expectancy after transfusion. RESULTS: Of all 2,405,012 blood product transfusions in the PROTON dataset, 92% was matched to the national Dutch Municipal Population Register, which registers all deaths. After 1 year, survival after any transfusion was 65·4%, 70·4% and 53·9% for RBC, FFP and PLT respectively. After 5 years, this was 46·6%, 58·8% and 39·3% for RBC, FFP and PLT, respectively. Ten years after transfusion, mortality rates of recipients are still elevated in comparison with the general population. CONCLUSION: Mortality rates of transfusion recipients are higher than those of the general population, but the increase diminishes over time. The mortality rates found for the Netherlands are lower than those found in comparable studies for other countries. |
| | |
Authors:
|
B A Borkent-Raven; M P Janssen; C L van der Poel; W P Schaasberg; G J Bonsel; B A van Hout |
Related Documents
:
|
17270777 - Real-time blood cross-matching sensor for intelligent management of transfusion safety. 20100667 - Specificity of 136 patient's antibodies to human red blood cells in dr. max peralta j h... 9128817 - The effect of blood transfusion and haemodilution on cerebral oxygenation and haemodyna... 10504117 - An investigation into the possibility of transmission of tick-borne pathogens via blood... 17270777 - Real-time blood cross-matching sensor for intelligent management of transfusion safety. 6167 - In vitro changes in blood p50 and erythrocyte 2,3-diphosphoglycerate concentration. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-08-18 |
Journal Detail:
|
Title: Vox sanguinis Volume: 100 ISSN: 1423-0410 ISO Abbreviation: Vox Sang. Publication Date: 2011 Feb |
Date Detail:
|
Created Date: 2011-01-12 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0413606 Medline TA: Vox Sang Country: England |
Other Details:
|
Languages: eng Pagination: 196-203 Citation Subset: IM |
Copyright Information:
|
© 2010 The Author(s). Vox Sanguinis © 2010 International Society of Blood Transfusion. |
Affiliation:
|
Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Prediction of low haemoglobin levels in whole blood donors.
Next Document: Research and development.