Document Detail

Survival after surgical treatment of breast cancer.
MedLine Citation:
PMID:  14985988     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The principle objective of locoregional treatment in breast cancer is to eradicate local disease in the breast and local lymph nodes. Surgery in breast cancer provides locoregional control of the disease by resection appropriate to oncological principles, i.e. complete resection with tumour-free margins. Type and extent of breast surgery is dependent on tumour stage; beyond that and even more importantly, prognosis of an individual patient depends upon its stage at diagnosis. METHOD: We reviewed the current literature, working out stage-specific survival and disease-free survival (DFS). The reported data were considered, according to stage and type of surgery, and a clear survey up to 20 years after surgery was depicted. Additionally, we assessed quality of life after breast cancer surgery. RESULTS: Overall survival (OS) rates after 5 years range from 93-84% in women diagnosed with stage I disease to 18% in women diagnosed with stage IV disease. In the management of stages I and II breast cancer, breast conservation with lumpectomy and radiation is a preferable alternative to mastectomy, with equivalent patient outcome. In stages III and IV breast cancer, surgery allows local control of the disease, but prognosis depends predominantly on the response to systemic treatment, as does prognosis in all breast cancer patients. CONCLUSION: The reported data distributing patients outcome according to stage and surgical treatment provide a clear summary in order to estimate an individual patient's risk.
Susanne Taucher; Raimund Jakesz
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Publication Detail:
Type:  Journal Article     Date:  2004-02-18
Journal Detail:
Title:  Langenbeck's archives of surgery / Deutsche Gesellschaft für Chirurgie     Volume:  389     ISSN:  1435-2443     ISO Abbreviation:  Langenbecks Arch Surg     Publication Date:  2004 Apr 
Date Detail:
Created Date:  2004-03-26     Completed Date:  2004-08-03     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9808285     Medline TA:  Langenbecks Arch Surg     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  75-82     Citation Subset:  IM    
Department of Surgery, Vienna University Medical School, Waehringer Guertel 18-20, 1090 Vienna, Austria.
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MeSH Terms
Breast Neoplasms / mortality,  pathology,  surgery*,  therapy
Carcinoma / mortality,  pathology,  surgery*,  therapy
Clinical Trials as Topic
Combined Modality Therapy
Lymph Node Excision / methods
Mastectomy / methods*
Neoplasm Metastasis
Neoplasm Staging
Quality of Life
Sentinel Lymph Node Biopsy / methods
Survival Analysis
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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