Document Detail

Survival after acute necrotizing eosinophilic myocarditis complicating a massive left ventricular mural thrombus: a case report.
MedLine Citation:
PMID:  17802696     Owner:  NLM     Status:  MEDLINE    
An 81-year-old man was referred to our hospital with exertional dyspnea following cold-like symptoms. Electrocardiography revealed ST elevation and positive T wave in leads I, II, aVL, aVF, and V2-V6. The diagnosis was acute myocarditis complicating heart failure. He was conservatively managed. On hospital day 8, brain infarction developed and echocardiography disclosed massive mural thrombus in the left ventricle. Left ventriculotomy was performed on hospital day 21 and histological examination showed inflammatory cell infiltration mainly composed of eosinophils and monocytes, degeneration of myocytes with replacement fibrosis, and fresh fibrin thrombus overlaying the endocardium. These findings were compatible with a diagnosis of acute necrotizing eosinophilic myocarditis(ANEM). He recovered uneventfully without specific therapy. This case suggests that a subtype of ANEM might be self-limiting.
Makoto Kontani; Shin-ichiro Takashima; Kiyotaka Okura; Hitoshi Takemori; Koji Maeno; Nobuyoshi Tanaka; Hirokazu Ohashi; Sakon Noriki
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of cardiology     Volume:  50     ISSN:  0914-5087     ISO Abbreviation:  J Cardiol     Publication Date:  2007 Aug 
Date Detail:
Created Date:  2007-09-06     Completed Date:  2007-10-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804703     Medline TA:  J Cardiol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  127-33     Citation Subset:  IM    
Department of Internal Medicine, Fukui-ken Saiseikai Hospital, Funabashi 7-1, Wadanaka-cho, Fukui, Fukui 918-8503.
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MeSH Terms
Aged, 80 and over
Eosinophilia / complications*,  pathology
Heart Diseases / etiology*,  surgery
Heart Ventricles / surgery*
Magnetic Resonance Imaging
Myocarditis / complications*,  diagnosis,  pathology,  surgery
Thrombosis / etiology*,  surgery
Ventricular Dysfunction, Left / etiology

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