Document Detail


Survival of hepatitis A virus in spinach during low temperature storage.
MedLine Citation:
PMID:  19903406     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Spinach leaves are frequently consumed raw and have been involved with past foodborne outbreaks. In this study, we examined the survival of hepatitis A virus (HAV) on fresh spinach leaves in moisture- and gas-permeable packages that were stored at 5.4 +/- 1.2 degrees C for up to 42 days. Different eluents including phosphate-buffered saline (PBS), pH 7.5 (with and without 2% serum), and 3% beef extract (pH 7.5 and 8) were compared for how efficiently they recovered viruses from spinach by using a simple elution procedure (<1 h). The recoveries were compared and determined by a plaque assay with FRhK-4 cells. Culture grade PBS containing 2% serum was found to be appropriate for HAV elution from spinach leaves, with an average recovery of 45% +/- 10%. Over 4 weeks of storage at 5.4 +/- 1.2 degrees C, HAV in spinach decreased slightly more than 1 log, with 6.75% of the original titer remaining. HAV survived under refrigerated temperatures on spinach leaves with a D-value of 28.6 days (equivalent to an inactivation rate of -0.035 log of HAV per day, r(2) = 0.88). In comparison, HAV in PBS containing 2% serum under the same storage conditions remained constant throughout 7 weeks. The inactivation rate of -0.035 log each day for HAV on spinach leaves was possibly due to the interaction of the virus and the leaf.
Authors:
Y Carol Shieh; Diana S Stewart; David T Laird
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of food protection     Volume:  72     ISSN:  0362-028X     ISO Abbreviation:  J. Food Prot.     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2009-11-11     Completed Date:  2010-01-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7703944     Medline TA:  J Food Prot     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2390-3     Citation Subset:  IM    
Affiliation:
U.S. Food and Drug Administration, National Center for Food Safety and Technology, Summit-Argo, Illinois 60501, USA. carol.shieh@fda.hhs.gov
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MeSH Terms
Descriptor/Qualifier:
Cold Temperature
Consumer Product Safety*
Culture Media / chemistry
Food Contamination / analysis*
Food Microbiology
Food Preservation / methods*
Hepatitis A virus / growth & development*,  isolation & purification
Humans
Hydrogen-Ion Concentration
Plant Leaves / virology
Public Health
Spinacia oleracea / virology*
Time Factors
Chemical
Reg. No./Substance:
0/Culture Media

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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