Document Detail

Survey of anthelmintic resistance on Danish horse farms, using 5 different methods of calculating faecal egg count reduction.
MedLine Citation:
PMID:  9705110     Owner:  NLM     Status:  MEDLINE    
This study reports on the prevalence of anthelmintic resistance in strongyles of horses in Denmark. Of 5 methods used for the calculation of faecal egg count reduction (FECR) the method recommended by the World Association for the Advancement of Veterinary Parasitology, for the detection of resistance in sheep was the most sensitive procedure for detecting resistance. Using this method benzimidazole resistance was detected on 33 of 42 farms (79%) examined. Pyrantel was tested on 15 farms and FECR tests indicate resistance on 3 (30%) farms. On 2 farms on which resistance to pyrantel was detected resistance to benzimidazoles was also detected. On one of 16 farms examined ivermectin resistance was indicated at Day 14 but not at Day 19. On the 15 remaining farms ivermectin was effective. Due to the high prevalence of anthelmintic resistance in Danish horse herds it is recommended that tests of anthelmintic efficacy be conducted routinely to monitor the effectiveness of the strongyle control programmes.
J Craven; H Bjørn; S A Henriksen; P Nansen; M Larsen; S Lendal
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Equine veterinary journal     Volume:  30     ISSN:  0425-1644     ISO Abbreviation:  Equine Vet. J.     Publication Date:  1998 Jul 
Date Detail:
Created Date:  1998-09-14     Completed Date:  1998-09-14     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0173320     Medline TA:  Equine Vet J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  289-93     Citation Subset:  IM    
Danish Veterinary Laboratory, Copenhagen V.
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MeSH Terms
Anthelmintics / pharmacology*,  therapeutic use
Drug Resistance
Feces / parasitology*
Fenbendazole / pharmacology,  therapeutic use
Follow-Up Studies
Ivermectin / pharmacology,  therapeutic use
Parasite Egg Count / methods,  veterinary*
Pyrantel Pamoate / pharmacology,  therapeutic use
Strongyle Infections, Equine / drug therapy*,  parasitology
Strongyloidea / drug effects*
Reg. No./Substance:
0/Anthelmintics; 22204-24-6/Pyrantel Pamoate; 43210-67-9/Fenbendazole; 70288-86-7/Ivermectin
Comment In:
Equine Vet J. 1998 Jul;30(4):280-3   [PMID:  9705108 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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