| A survey of the management, control, and complications of diabetes mellitus in patients attending a diabetes clinic in Blantyre, Malawi, an area of high HIV prevalence. | |
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MedLine Citation:
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PMID: 20810823 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of this study was to describe the current status of diabetes care in an urban diabetes clinic in Malawi and the prevalence of human immunodeficiency virus (HIV) in this population, investigating possible associations between HIV and diabetes. A systematic prospective survey of patients attending the diabetes clinic at a teaching hospital in Blantyre, Malawi was conducted. Six hundred twenty patients were assessed. Seventy-four percent had glycosylated hemoglobin (HbA1C) > 7.5%. Systolic blood pressure was > 140 mm Hg in 52% of patients. Hypertension was more common in patients with raised creatinine (P < 0.003), retinopathy (P = 0.01), and stroke (P < 0.0002). Microvascular complication rates were high, specifically nephropathy (34.7%), retinopathy (34.7%), and neuropathy (46.4%). HIV seroprevalence was 13.7%. HIV-positive subjects had a lower body mass index (BMI) and lower fasting blood sugar, and they were more likely to have albuminuria (48.0% versus 33.3%; P < 0.05). Control of glycemia and hypertension were poor, and microvascular complications were common. Nephropathy in diabetic patients may be affected by HIV status. |
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Authors:
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Danielle B Cohen; Theresa J Allain; Simon Glover; Daniel Chimbayo; Helen Dzamalala; Helma W C Hofland; Ndaziona P K Banda; Eduard E Zijlstra |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The American journal of tropical medicine and hygiene Volume: 83 ISSN: 1476-1645 ISO Abbreviation: Am. J. Trop. Med. Hyg. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-09-02 Completed Date: 2010-09-27 Revised Date: 2011-09-13 |
Medline Journal Info:
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Nlm Unique ID: 0370507 Medline TA: Am J Trop Med Hyg Country: United States |
Other Details:
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Languages: eng Pagination: 575-81 Citation Subset: AIM; IM |
Affiliation:
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Department of Medicine, College of Medicine, University of Malawi, Blantyre, Malawi. danbcohen@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Diabetes Complications Diabetes Mellitus / therapy* Female HIV Infections / complications* HIV Seroprevalence* Hemoglobin A, Glycosylated / analysis Humans Hypertension / complications, drug therapy Malawi / epidemiology Male Middle Aged Prospective Studies Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Hemoglobin A, Glycosylated |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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