Document Detail


Surveillance of congenital rubella syndrome in Japan, 1978-2002: effect of revision of the immunization law.
MedLine Citation:
PMID:  15364460     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Infection of rubella virus at the early stages of pregnancy in women who are not immune to rubella often induces congenital anomalies in infants, namely congenital rubella syndrome (CRS). This paper is the first comprehensive report of CRS cases in Japan, compiled from a questionnaire to major hospitals, reports to journals and academic meetings, and cases for virus/virus genome verification submitted to the National Institute of Infectious Diseases. CRS incidence in Japan was determined to be 0.2-8.1 cases/100,000 live births per year in epidemic years and 0.1-0.7 in non-epidemic years, respectively. In the last 4 years, the number of CRS cases remarkably decreased to one-three cases per year. This decrease is thought to be because the immunization law was revised in 1994 for changing the focus of rubella immunization from junior high school girls to infants of both sexes.
Authors:
Shigetaka Katow
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Vaccine     Volume:  22     ISSN:  0264-410X     ISO Abbreviation:  Vaccine     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-09-14     Completed Date:  2005-03-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8406899     Medline TA:  Vaccine     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  4084-91     Citation Subset:  IM    
Affiliation:
Department of Virology III, National Institute of Infectious Diseases, Japan. sqk6@cdc.gov
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MeSH Terms
Descriptor/Qualifier:
Female
Humans
Immunization Programs / legislation & jurisprudence*
Incidence
Japan / epidemiology
Pregnancy
Pregnancy Complications, Infectious / diagnosis,  epidemiology
Pregnancy Trimesters
Questionnaires
Rubella / diagnosis,  epidemiology
Rubella Syndrome, Congenital / epidemiology*,  pathology
Rubella Vaccine* / immunology
Chemical
Reg. No./Substance:
0/Rubella Vaccine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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