Document Detail

Surmounting Chemoresistance by Targeting the Y-Box Binding Protein-1.
MedLine Citation:
PMID:  22190445     Owner:  NLM     Status:  Publisher    
The Y-box binding protein 1 (YB-1), characterized by the presence of the cold shock domain, has been reported to induce chemoresistance in cancer therapy. Chemotherapy is one of the main therapeutic strategies in the treatment of cancer, in addition to surgery, radiation therapy, and hormonal therapy. However, chemoresistance remains a key obstacle to successful cancer management. In this review, we will focus on the role of YB-1, an important regulator of gene transcription, in cancer therapy and chemoresistance. Anat Rec, 2011. © 2011 Wiley Periodicals, Inc.
Ikuyo Inoue; Ken Matsumoto; Yingnan Yu; Boon-Huat Bay
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-12-20
Journal Detail:
Title:  Anatomical record (Hoboken, N.J. : 2007)     Volume:  -     ISSN:  1932-8494     ISO Abbreviation:  -     Publication Date:  2011 Dec 
Date Detail:
Created Date:  2011-12-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101292775     Medline TA:  Anat Rec (Hoboken)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 Wiley Periodicals, Inc.
Department of Anatomy, Yong Loo Lin School of Medicine, National University Health System, National University of Singapore, Singapore.
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