Document Detail


Surgical treatment of renovascular hypertension.
MedLine Citation:
PMID:  921527     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two hundred sixty-four patients exhibiting renal artery occlusive disease underwent operation for renovascular hypertension between 1961 and 1977. Included were 27 pediatric patients. Fibrodysplastic disease affected 132 adults. Atherosclerotic lesions affected 51 patients with and 54 patients without clinically overt extrarenal arteriosclerotic cardiovascular disease. Ischemic kidney renin hypersecretion (renal: systemic index greater than 0.48), associated with suppressed contralateral kidney renin secretion (renal: systemic index approaching 0.0) predicted curability most reliably. Three hundred forty-eight operations were performed, of which 297 were primary and 51 were secondary procedures. Nephrectomy was initial therapy in 15 cases. Three operative deaths occurred among 51 patients manifesting overt extrarenal arteriosclerotic disease. No operative mortality was encountered among the other 213 patients. Surgical benefits were afforded 96% of pediatric patients and adults with fibrodysplastic disease, 91% of patients with focal renal arteriosclerosis, and 73% of those exhibiting overt extrarenal arteriosclerosis.
Authors:
J C Stanley; W J Fry
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of surgery (Chicago, Ill. : 1960)     Volume:  112     ISSN:  0004-0010     ISO Abbreviation:  Arch Surg     Publication Date:  1977 Nov 
Date Detail:
Created Date:  1977-12-29     Completed Date:  1977-12-29     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9716528     Medline TA:  Arch Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1291-7     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aorta / surgery
Arteriosclerosis / complications
Blood Pressure
Child
Female
Humans
Hypertension, Renal / surgery*
Male
Middle Aged
Nephrectomy
Renal Artery / surgery*
Renal Artery Obstruction / etiology,  surgery*
Renin / blood
Surgical Procedures, Operative / mortality
Chemical
Reg. No./Substance:
EC 3.4.23.15/Renin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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