| Surgical treatment of obesity. | |
| | |
MedLine Citation:
|
PMID: 17643128 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Obesity is very prevalent. Most treatments fail owing to hard-wired survival mechanisms, linking stress and appetite, which have become grossly maladaptive in the industrial era. Antiobesity (bariatric) surgery is a seemingly drastic, efficacious therapy for this serious disease of energy surfeit. Technical progress during the last two decades has greatly improved its safety. The surgical principles of gastric restriction and/or gastrointestinal diversion have remained largely unchanged over 40 years, although mechanisms of action have been elucidated concomitant with advances in knowledge of the molecular biology of energy balance and appetite regulation. Results of bariatric surgery in large case-series followed for at least 10 years consistently demonstrate amelioration of components of the insulin-resistance metabolic syndrome and other comorbidities, significantly improving quality of life. Furthermore, bariatric surgery has convincingly been demonstrated to reduce mortality compared with nonoperative methods. This surgery requires substantial preoperative and postoperative evaluation, teaching, and monitoring to optimize outcomes. In the absence of effective societal changes to restore a healthy energy balance, bariatric surgery is an important tool for treating a very serious disease. |
| | |
Authors:
|
John G Kral; Erik Näslund |
Related Documents
:
|
17606028 - Preoperative and postoperative management of obstructive sleep apnea patients. 16687038 - Six steps to fast-track insurance approval for bariatric surgery. 9730398 - Converting vertical banded gastroplasty to a lesser curvature gastric bypass: technical... 20124768 - Status of bariatric surgery in germany--results of the nationwide survey on bariatric s... 4073768 - The surgical treatment of gastroduodenal crohn's disease. 12209298 - Open mesh plug hernioplasty in ambulatory surgery: a study of feasibility based on our ... |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Nature clinical practice. Endocrinology & metabolism Volume: 3 ISSN: 1745-8374 ISO Abbreviation: - Publication Date: 2007 Aug |
Date Detail:
|
Created Date: 2007-07-23 Completed Date: 2007-08-09 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 101261798 Medline TA: Nat Clin Pract Endocrinol Metab Country: England |
Other Details:
|
Languages: eng Pagination: 574-83 Citation Subset: IM |
Affiliation:
|
Department of Surgery, State University of New York Downstate Medical Center, Brooklyn, NY 11203-2098, USA. jkral@downstate.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Bariatric Surgery
/
adverse effects,
economics,
methods* Cost-Benefit Analysis Humans Obesity, Morbid / physiopathology, surgery* Patient Education as Topic Patient Selection Quality of Life Risk Factors Treatment Outcome Weight Loss / physiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The ins and outs of the plant cell cycle.
Next Document: Drug insight: breast cancer prevention and tissue-targeted hormone replacement therapy.