| Surgical treatment of low- and intermediate-risk papillary thyroid cancer with minimally invasive video-assisted thyroidectomy. | |
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MedLine Citation:
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PMID: 19223525 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Minimally invasive video-assisted thyroidectomy (MIVAT) was introduced in the clinical practice to treat small benign thyroid nodules. This method has recently been demonstrated to produce the same completeness as a conventional thyroidectomy in patients with papillary thyroid cancer (PTC). The low number of treated cases and the limited follow-up of these patients represent the major limitations of these studies. OBJECTIVE: The aim of the study was to compare the outcome of two groups of PTC patients, one treated with MIVAT and the other with conventional thyroidectomy, after a median follow-up of 5 yr. STUDY GROUP: A total of 221 PTC patients were enrolled in this study according to the following criteria: 171 were treated with MIVAT (group A), and 50 were treated with conventional thyroidectomy (group B). RESULTS: The outcome and the cumulative (131)I activity administered to achieve curative status were compared. After a mean follow-up of 3.6 +/- 1.5 yr (range, 1-8 yr; median, 5 yr), no differences were found between group A and group B. A similar rate of permanent hypoparathyroidism and/or nerve cord palsy was found in both groups. CONCLUSION: We demonstrated that PTC patients operated on with MIVAT had a good outcome after 5 yr. This was similar to the outcome of patients treated with conventional thyroidectomy and the same degree of exposure to (131)I. These results, together with the evidence of a similar degree of completeness and rate of complications between the two surgical techniques, show that MIVAT is a valid option to treat low- and intermediate-risk PTC patients. |
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Authors:
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Paolo Miccoli; Aldo Pinchera; Gabriele Materazzi; Agnese Biagini; Piero Berti; Pinuccia Faviana; Eleonora Molinaro; David Viola; Rossella Elisei |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2009-02-17 |
Journal Detail:
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Title: The Journal of clinical endocrinology and metabolism Volume: 94 ISSN: 1945-7197 ISO Abbreviation: J. Clin. Endocrinol. Metab. Publication Date: 2009 May |
Date Detail:
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Created Date: 2009-05-07 Completed Date: 2009-05-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375362 Medline TA: J Clin Endocrinol Metab Country: United States |
Other Details:
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Languages: eng Pagination: 1618-22 Citation Subset: AIM; IM |
Affiliation:
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Department of Surgery, University of Pisa, Via Roma 64, 56100 Pisa, Italy. p.miccoli@dc.med.unipi.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Carcinoma, Papillary / pathology, radiotherapy, surgery* Child Female Follow-Up Studies Humans Hypoparathyroidism / epidemiology, etiology Iodine Radioisotopes / therapeutic use Male Middle Aged Paralysis / epidemiology, etiology Postoperative Complications / epidemiology Risk Surgical Procedures, Minimally Invasive / adverse effects, methods* Thyroid Neoplasms / pathology, radiotherapy, surgery* Thyroidectomy / adverse effects, methods* Treatment Outcome Video-Assisted Surgery / adverse effects, methods* Young Adult |
| Chemical | |
Reg. No./Substance:
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0/Iodine Radioisotopes |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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