Document Detail


Surgical treatment of infective endocarditis.
MedLine Citation:
PMID:  7570682     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
From February, 1975 through October, 1990, 26 patients underwent surgical treatment for infective endocarditis at Tokai University Hospital. The overall operative mortality rate was 11.5% (3/26). The three patients who died were suffering from aortic prosthetic valve endocarditis (PVE) in the active stage. Among 16 patients in the active stage, the mortality rate was 18.7% (3/16) Among 10 patients with native valve endocarditis (NVE) in the healed stage, all survived. Among the total of 21 patients with NVE, the mortality rate was zero and among those with PVE, the rate was 60% (3/5). Various species of streptococci were the most common organisms encountered, followed by Staphylococcus epidermides. The two PVE patients with S. epidermides died. Nine of the 11 NVE cases in the active stage were of the localized type. Only one case of the localized type of PVE suffered from an infected mitral bioprosthetic valve. The 6 extensive-type cases had aortic valve endocarditis (2NVE, 4PVE). Three patients with the extensive type of PVE died. We conclude that patients with infective endocarditis who develop progressive congestive heart failure, recurrent embolization, or progressive sepsis despite antimicrobial treatments, should undergo prompt valve replacement within 7 days after institution of therapy.
Authors:
K Kanabuchi; S Inamura; S Odagiri; S Koide; A Shohtsu
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Tokai journal of experimental and clinical medicine     Volume:  19     ISSN:  0385-0005     ISO Abbreviation:  Tokai J. Exp. Clin. Med.     Publication Date:  1994 Dec 
Date Detail:
Created Date:  1995-10-20     Completed Date:  1995-10-20     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7704186     Medline TA:  Tokai J Exp Clin Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  121-4     Citation Subset:  IM    
Affiliation:
First Department of Surgery, Tokai University School of Medicine, Kanagawa, Japan.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Anti-Bacterial Agents / therapeutic use
Aortic Valve
Child
Endocarditis, Bacterial / drug therapy,  mortality,  surgery*
Female
Heart Valve Prosthesis / adverse effects,  mortality
Humans
Male
Middle Aged
Mitral Valve
Staphylococcal Infections / mortality,  surgery
Staphylococcus epidermidis
Streptococcal Infections / mortality,  surgery
Chemical
Reg. No./Substance:
0/Anti-Bacterial Agents

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