Document Detail

Surgical treatment for Löffler's endocarditis with left ventricular thrombus and severe mitral regurgitation: a case report.
MedLine Citation:
PMID:  16637255     Owner:  NLM     Status:  MEDLINE    
A 65-year-old female was admitted to our hospital because of dyspnea. Laboratory examinations revealed hypereosinophilia at a local hospital. Transthoracic and transesophageal echocardiography showed normal left ventricular dimension and function. The left ventricular apex was obliterated and the posterior and lateral walls were thickened by an abnormal mass. The posterior mitral leaflet was encapsulated by this abnormal mass. The limited motion of the posterior mitral leaflet caused mitral malcoaptation, resulting in severe mitral regurgitation. Hypereosinophilia was considered to be idiopathic, as no other disorders known to cause secondary eosinophilia were found. No other organ dysfunction was associated with the condition. Thus, the diagnosis was Loffler's endocarditis associated with hypereosinophilic syndrome. The patient was given conservative medical treatment immediately on admission. However, heart failure caused by mitral regurgitation would be difficult to treat with conservative medical treatment, so we chose a surgical strategy. The symptoms obviously improved after valve replacement and removal of the abnormal mass, and the patient was discharged. However, she died of cerebral infarction at a local hospital 3 months later.
Hidekazu Tanaka; Hiroya Kawai; Kazuhiro Tatsumi; Toshiya Kataoka; Tetsuari Onishi; Takahisa Nose; Takahiro Mizoguchi; Mitsuhiro Yokoyama; Yutaka Okita
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of cardiology     Volume:  47     ISSN:  0914-5087     ISO Abbreviation:  J Cardiol     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-04-26     Completed Date:  2006-05-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804703     Medline TA:  J Cardiol     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  207-13     Citation Subset:  IM    
Division of Cardiovascular and Respiratory Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe.
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MeSH Terms
Heart Diseases / surgery*
Heart Valve Prosthesis Implantation*
Heart Ventricles
Hypereosinophilic Syndrome / surgery*,  ultrasonography
Mitral Valve / surgery
Mitral Valve Insufficiency / surgery*
Thrombosis / surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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