Document Detail

Surgical treatment of complex intracranial aneurysms.
MedLine Citation:
PMID:  18695549     Owner:  NLM     Status:  MEDLINE    
Complex intracranial aneurysms include not only giant aneurysms (classically larger than 25 mm in diameter) but also smaller aneurysms in difficult locations of the human brain and cranial base. Such lesions are associated with a high risk of subarachnoid hemorrhage and progressive neurological deterioration or death caused by mass effect or stroke. In the past 30 years, the understanding and treatment of these lesions have progressed considerably. Nonetheless, a deep understanding of these lesions, including the nuances of blood flow dynamics, natural history, and potential therapeutic options, is necessary when one is managing such aneurysms. The senior author's (RFS) clinical experience with more than 5000 brain aneurysms was reviewed. We also reviewed recent literature on the surgical management of giant cerebral aneurysms, focusing on the most up-to-date microsurgical techniques. Combinations of therapies can be used in an attempt to provide a solution to various clinical dilemmas associated with the management of these difficult lesions. The synergistic association between microsurgery and endovascular modalities is also illustrated. On the basis of the knowledge obtained over the years, indirect and multimodality approaches are becoming more common as neurosurgeons strive to improve patient outcomes.
Ricardo A Hanel; Robert F Spetzler
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Neurosurgery     Volume:  62     ISSN:  1524-4040     ISO Abbreviation:  Neurosurgery     Publication Date:  2008 Jun 
Date Detail:
Created Date:  2008-08-12     Completed Date:  2008-10-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802914     Medline TA:  Neurosurgery     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1289-97; discussion 1297-9     Citation Subset:  IM    
Department of Neurosurgery, Mayo Clinic, Jacksonville, Florida, USA.
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MeSH Terms
Cerebrum / surgery
Intracranial Aneurysm / surgery*
Neurosurgical Procedures / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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