Document Detail

Surgical treatment of chronic thromboembolic pulmonary hypertension.
MedLine Citation:
PMID:  16947087     Owner:  NLM     Status:  MEDLINE    
Chronic thromboembolic pulmonary hypertension is a commonly overlooked cause of physical incapacity and dyspnoea, with a higher incidence than is generally appreciated and a poor prognosis. The diagnosis can be suspected based on echocardiographic examinations and ventilation perfusion scanning of the lung. Pulmonary angiography still remains the gold standard for the diagnosis of thromboembolic pulmonary hypertension and the assessment of operability. Pulmonary endarterectomy is a complex surgical procedure, which provides permanent relief of thromboembolic pulmonary hypertension and cure for most of the patients. The operation resembles a true endarterectomy of the pulmonary artery branches using extracorporeal circulation and periods of hypothermic circulatory arrest. In experienced centres, the operative risk has been decreased to an acceptable level. Following successful surgery, long-term survival and quality of life are excellent. Earlier referral to surgery might avoid the occurrence of a secondary vasculopathy in the unaffected areas of the pulmonary vascular tree, and therefore further improve early and late results. A multidisciplinary approach and surgical experience are the prerequisites for success of this demanding procedure.
Eckhard Mayer
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Swiss medical weekly     Volume:  136     ISSN:  1424-7860     ISO Abbreviation:  Swiss Med Wkly     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-09-01     Completed Date:  2006-12-05     Revised Date:  2011-02-15    
Medline Journal Info:
Nlm Unique ID:  100970884     Medline TA:  Swiss Med Wkly     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  491-7     Citation Subset:  IM    
Department of Cardiothoracic and Vascular Surgery, Johannes Gutenberg Univesity Hospital, Mainz, Germany.
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MeSH Terms
Chronic Disease
Hypertension, Pulmonary / complications,  surgery*
Lung Transplantation
Pulmonary Embolism / etiology,  surgery*
Thromboembolism / etiology,  surgery*

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