Document Detail

Surgical treatment of carcinoma of the hepatic duct confluence: analysis of 55 resected carcinomas.
MedLine Citation:
PMID:  8447147     Owner:  NLM     Status:  MEDLINE    
We treated 65 patients with carcinoma of the hepatic duct confluence between 1976 and 1991, 57 (87.7%) of whom were treated surgically; of the 57, 55(96.5%) underwent resection. Radical resection was performed at a rate of 50.9%. Procedures for these 55 patients included resection of the extrahepatic bile duct plus hepatectomy (n = 33; 60.0%), and resection of the duct without hepatectomy (n = 22; 40.0%). In addition, the caudate lobe was resected in 28 of these patients, and the portal vein, hepatic artery, or both were resected in 6. The overall operative morbidity was 21.8%; morbidity occurred in 33.3% of patients with hepatectomy, a significantly higher percent than the 4.5% rate in those without hepatectomy (p < 0.05). Operative death occurred in only 1.9%. As the depth of cancer invasion in the bile duct wall advanced, the incidence of tumor spread (e.g., lymphatic permeation, venous invasion, perineural invasion, lymph node metastasis) increased significantly. The prevalence of extramural tumor extensions in a transverse direction was higher than that in the longitudinal direction along the bile duct wall; and the distance from the margin of the primary tumor to the site of tumor extensions along the bile duct wall was much longer on the hepatic side than on the duodenal side. Cancer invasion of the caudate lobe was observed in 36.4%, and invasion at the surgical margins was found more frequently in those without hepatectomy than those with hepatectomy.(ABSTRACT TRUNCATED AT 250 WORDS)
Y Ogura; R Mizumoto; M Tabata; S Matsuda; T Kusuda
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  World journal of surgery     Volume:  17     ISSN:  0364-2313     ISO Abbreviation:  World J Surg     Publication Date:    1993 Jan-Feb
Date Detail:
Created Date:  1993-04-07     Completed Date:  1993-04-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7704052     Medline TA:  World J Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  85-92; discussion 92-3     Citation Subset:  IM    
First Department of Surgery, Mie University School of Medicine, Tsu, Japan.
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MeSH Terms
Aged, 80 and over
Bile Duct Neoplasms / mortality,  surgery*
Hepatic Duct, Common* / surgery
Middle Aged
Survival Rate

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