Document Detail


Surgical treatment of Takayasu's arteritis: case report and literature review.
MedLine Citation:
PMID:  10742426     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Surgical intervention during the early stages of Takayasu's arteritis is rarely necessary. In the chronic stages of this disease, however, surgeons may be faced with difficult decisions regarding the timing of complex arterial reconstructions. These issues can be especially challenging in the pediatric population. We report the case of an 8-year-old girl with chronic Takayasu's arteritis complicated by malignant hypertension. Despite aggressive medical therapy, her blood pressure remained uncontrolled. Imaging studies demonstrated infrarenal aortic and right common iliac artery aneurysms with concomitant segmental stenosis of the right common iliac artery. Since her transplant kidney was based off the right external iliac artery, it was felt that this high-grade stenosis was responsible for her severe hypertension. Immediate surgical reconstruction was therefore recommended. Intraoperatively, the aneurysmal aorta and iliac arteries were found to be densely calcified. The transplant kidney was perfused during aortic clamping by placement of a suprarenal aorta to the right external iliac artery shunt. Endoaneurysmorrhaphy was then performed to reconstruct the aorta after extensive endarterectomy. In the early postoperative period, antihypertensive medications were decreased to two oral agents. She was discharged on the seventh postoperative day and placed on two agents. At a 1-year follow-up visit, she is on one antihypertensive medication. Her right leg complaints have resolved. Ultrasound surveillance revealed no evidence of recurrent aneurysmal or occlusive disease. A brief review of complications related to Takayasu's arteritis in the children and indications for surgical intervention completes this report.
Authors:
S R Sparks; A Chock; S Seslar; J J Bergan; E L Owens
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Annals of vascular surgery     Volume:  14     ISSN:  0890-5096     ISO Abbreviation:  Ann Vasc Surg     Publication Date:  2000 Mar 
Date Detail:
Created Date:  2000-05-12     Completed Date:  2000-05-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8703941     Medline TA:  Ann Vasc Surg     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  125-9     Citation Subset:  IM    
Affiliation:
Section of Vascular Surgery, University of California-San Diego Medical Center, San Diego, CA 92103, USA.
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MeSH Terms
Descriptor/Qualifier:
Antihypertensive Agents / therapeutic use
Aortic Aneurysm, Abdominal / etiology,  radiography,  surgery
Child
Endarterectomy
Female
Humans
Hypertension, Malignant / drug therapy,  etiology
Iliac Aneurysm / etiology,  radiography,  surgery
Kidney Transplantation
Takayasu Arteritis / complications,  surgery*
Chemical
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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