Document Detail

Surgical therapy for osteonecotic lesions of the jaws in patients in therapy with bisphosphonates.
MedLine Citation:
PMID:  17912074     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Surgical therapy to improve the symptoms and the lesions in osteonecrosis (ON) of the jaws in patients in therapy with bisphosphonates.
DESIGN: to evaluate the patient's therapeutic protocols, performance status, and factors promoting ON to prevent surgical failure.
MATERIALS AND METHODS: 18 patients affected by osteonecrotic lesions of the jaws associated to BF, were treated by surgery.
RESULTS: The results were recorded after 6 months. All the patients showed improvement of symptoms, in particular the pain. In addition, all the patients referred to a sensation of fresh and clean mouth, the disappearance of fetor ex ore, and a healthy mouth.
CONCLUSIONS: The management and the resolution of BF osteonecrotic lesions is arguable and complex because in most cases, the patients are affected by oncologic disease when the better approach is prevention, but when the ON lesion is clear, surgery can improve the symptoms and in some cases, it can be resolute. To prevent surgical failure, it can be useful to evaluate the patient's therapeutic protocols, performance status, and factors promoting ON.
Gianluigi Longobardi; Roberto Boniello; Giulio Gasparini; Immacolata Pagano; Sandro Pelo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of craniofacial surgery     Volume:  18     ISSN:  1049-2275     ISO Abbreviation:  J Craniofac Surg     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-10-03     Completed Date:  2007-12-06     Revised Date:  2014-07-30    
Medline Journal Info:
Nlm Unique ID:  9010410     Medline TA:  J Craniofac Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1012-7     Citation Subset:  D    
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MeSH Terms
Bone Density Conservation Agents / adverse effects*
Diphosphonates / adverse effects*
Jaw Diseases / chemically induced,  surgery*
Middle Aged
Osteonecrosis / chemically induced,  surgery*
Reg. No./Substance:
0/Bone Density Conservation Agents; 0/Diphosphonates

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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