| Surgical therapy of lesions within the hypothalamic region. | |
| | |
MedLine Citation:
|
PMID: 3993448 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
On one hand pituitary microadenomas with autonomous character and those, which had been influenced by hypothalamic disorders, are summarized and discussed. On the other hand, the neurosurgical management of tumours, adjacent to or involved with the hypothalamus, are described. Endocrinologically active pituitary adenomas are characterized by their hormone excess of ACTH, GH, and prolactin. In Cushing's disease endocrine and clinical remission occurred in 74%. 3 patients out of this group showed a reincrease of ACTH after a period of remission, indicating a possible hypothalamic influence. In acromegaly the hypothalamic influence is also discussed. One patient with an ectopic GRF-producing tumour showing a reincrease of GH levels after successful transsphenoidal adenomectomy has been described. In microprolactinomas, 7 patients out of 45 showed a reincrease of prolactin-levels after a period of normalization, we also discussed hypothalamic disorders. Tumours with suprasellar extension such as macroadenomas without endocrine activity and meningiomas are removed nowadays with minimal risk for the life of the patients. In craniopharyngiomas radical excision is accompanied by a high risk of hypothalamic defects caused by mechanical lesions and possible secondary vasospasm. Finally the excision of a hamartoma growing from the floor of the third ventricle into the interpeduncular cistern is discussed. Up to now the successful excision could be documented by endocrinological data, which give no sign of further growth of the hamartoma. |
| | |
Authors:
|
R Fahlbusch; U Schrell |
Related Documents
:
|
1089928 - Diagnostic use of luteinizing hormone releasing hormone in primary amenorrhea. 2545768 - Bilateral and simultaneous venous sampling of inferior petrosal sinuses for acth and pr... 6280898 - The steroid response to controlled adrenal stimulation in congenital adrenal hyperplasia. 10528818 - Psychopathology in alcohol withdrawal: relationship to alpha2-adrenoceptor function. 22738688 - Role of transthoracic left atrial appendage wall motion velocity in patients with persi... 697178 - Radioisotope scanning in the initial staging of bronchogenic carcinoma. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Acta neurochirurgica Volume: 75 ISSN: 0001-6268 ISO Abbreviation: Acta Neurochir (Wien) Publication Date: 1985 |
Date Detail:
|
Created Date: 1985-06-06 Completed Date: 1985-06-06 Revised Date: 2009-11-11 |
Medline Journal Info:
|
Nlm Unique ID: 0151000 Medline TA: Acta Neurochir (Wien) Country: AUSTRIA |
Other Details:
|
Languages: eng Pagination: 125-35 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acromegaly
/
surgery Adenoma / surgery Astrocytoma / surgery Brain Neoplasms / surgery Craniopharyngioma / surgery Cushing Syndrome / surgery Female Follow-Up Studies Humans Hypothalamic Diseases / surgery* Hypothalamic Hormones / blood Male Meningeal Neoplasms / surgery Meningioma / surgery Pituitary Hormones / blood Pituitary Neoplasms / surgery Prolactin / secretion Puberty, Precocious / surgery |
| Chemical | |
Reg. No./Substance:
|
0/Hypothalamic Hormones; 0/Pituitary Hormones; 9002-62-4/Prolactin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Vegetative dysfunctions of the hypothalamus.
Next Document: Tumours of the third ventricle.