Document Detail


Surgical strategies for the prevention of gastrointestinal tumours
MedLine Citation:
PMID:  15765298     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Over many decades the surgical treatment of gastrointestinal tumours was limited to cases of manifest malignancy and was performed with curative or palliative intent. Molecular diagnostics have now led to an optimised characterisation of different sporadic and hereditary tumour entities. Furthermore, a number of diseases which are an obligatory precancerosis or which carry a very high risk of cancer in their long courses have now been identified. Parallel to these developments, a dramatic reduction of morbidity has been achieved in major abdominal surgery due to more subtle and blood-sparing surgical techniques and mortality has been reduced to a minimum even in the most major procedures. This combination nowadays safely allows preventive or preventive extended surgical measures in cases where interventional therapy cannot be adequately employed.
Authors:
H-P Knaebel; P Kienle; M W Büchler; J Weitz
Publication Detail:
Type:  Comparative Study; English Abstract; Journal Article    
Journal Detail:
Title:  Zeitschrift für Gastroenterologie     Volume:  43     ISSN:  0044-2771     ISO Abbreviation:  Z Gastroenterol     Publication Date:  2005 Mar 
Date Detail:
Created Date:  2005-03-14     Completed Date:  2005-05-09     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0033370     Medline TA:  Z Gastroenterol     Country:  Germany    
Other Details:
Languages:  ger     Pagination:  257-66     Citation Subset:  IM    
Affiliation:
Abteilung für Allgemein-, Viszeral- und Unfallchirurgie, Chirurgische Universitätsklinik Heidelberg. Hanns-Peter_Knaebel@med.uni-heidelberg.de
Vernacular Title:
Chirurgische Ansätze zur Prävention bei gastrointestinalen Tumoren.
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MeSH Terms
Descriptor/Qualifier:
Adenomatous Polyposis Coli / diagnosis,  genetics,  surgery*
Adolescent
Adult
Aged
Child
Chronic Disease
Colitis, Ulcerative / diagnosis,  surgery*
Colorectal Neoplasms, Hereditary Nonpolyposis / diagnosis,  genetics,  surgery*
Female
Gastrointestinal Neoplasms / prevention & control*
Genotype
Humans
Immunohistochemistry
Male
Middle Aged
Mutation
Pancreatitis / diagnosis,  surgery*
Phenotype
Precancerous Conditions / surgery*
Proctocolectomy, Restorative
Recurrence
Risk Factors
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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