| Surgical and percutaneous myocardial angiogenesis induction. Part II--neoangiogenesis. | |
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MedLine Citation:
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PMID: 11214697 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Coronary artery bypass surgery and angioplasty provide symptomatic relief in patients with ischemic heart disease, but despite advancement in technique and devices, these methods are not applicable to a subset of patients with angina refractory to medical treatment. Bypass surgery might not be feasible because of lack of suitable conduits, diffuse coronary disease or poor distal run-off, and coronary angioplasty is sometimes not applicable due to chronic total occlusion, diffuse disease or extreme tortuosity. We have previously reviewed the available experience with laser-induced direct myocardial revascularization, one of the new potential treatment modalities for this patient subset. One of the potential mechanisms of action for laser treatment is the induction of neoangiogenesis. In the second part of our article we review the available experience with the induction of myocardial angiogenesis using different growth factors or the genes encoding for them. |
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Authors:
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G Gimelli; C Di Mario; F Liistro; A V Dharmadhikari; M Montorfano; A Anzuini; M Vaghetti; M Puchala-Borowik; F Airoldi; M Carlino; V Tzifos; F Maisano; O Alfieri; A Colombo |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Italian heart journal : official journal of the Italian Federation of Cardiology Volume: 2 ISSN: 1129-471X ISO Abbreviation: Ital Heart J Publication Date: 2001 Jan |
Date Detail:
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Created Date: 2001-02-14 Completed Date: 2001-06-07 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 100909716 Medline TA: Ital Heart J Country: Italy |
Other Details:
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Languages: eng Pagination: 21-4 Citation Subset: IM |
Affiliation:
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Department of Interventional Cardiology, Columbus Hospital, Milan, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Coronary Disease
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drug therapy*,
physiopathology Disease Models, Animal Endothelial Growth Factors / physiology, therapeutic use* Fibroblast Growth Factors / physiology Gene Therapy / methods Humans Lymphokines / therapeutic use Neovascularization, Physiologic / physiology* Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factors |
| Chemical | |
Reg. No./Substance:
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0/Endothelial Growth Factors; 0/Lymphokines; 0/Vascular Endothelial Growth Factor A; 0/Vascular Endothelial Growth Factors; 62031-54-3/Fibroblast Growth Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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