Document Detail

Surgical pathology of epilepsy: a review.
MedLine Citation:
PMID:  7971589     Owner:  NLM     Status:  MEDLINE    
This review discusses the neuropathological issues pertaining to temporal lobectomies and neocortical resections for medically refractory seizures of childhood. Most cases in our pediatric series are "lesional" and have CT/MRI abnormalities that contribute to a higher incidence of "dual pathology" lesions rather than pure mesial temporal sclerosis. Almost up to two thirds of our cases are represented by neuronal migration disorders and low grade gliomas. We have also encountered lesions that have both neoplastic and malformative foci, some of which behave more like tumors, while others defy precise classification as tumor or malformation. Our preliminary data indicate a role for cytomegalovirus in some cases of Rasmussen's encephalitis.
V Jay; L E Becker
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Pediatric pathology / affiliated with the International Paediatric Pathology Association     Volume:  14     ISSN:  0277-0938     ISO Abbreviation:  Pediatr Pathol     Publication Date:    1994 Jul-Aug
Date Detail:
Created Date:  1994-12-12     Completed Date:  1994-12-12     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8303527     Medline TA:  Pediatr Pathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  731-50     Citation Subset:  IM    
Department of Pathology, Hospital for Sick Children, University of Toronto, Ontario, Canada.
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MeSH Terms
Brain Neoplasms / pathology,  surgery
Cerebral Cortex / pathology,  surgery
Child, Preschool
Epilepsy / classification,  pathology*,  surgery*
Ganglioglioma / pathology,  surgery
Glioma / pathology,  surgery
Infant, Newborn
Magnetic Resonance Imaging
Temporal Lobe / pathology,  surgery

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