Document Detail

Surgical pathology of combined aortic stenosis and insufficiency: a study of 213 cases.
MedLine Citation:
PMID:  3982077     Owner:  NLM     Status:  MEDLINE    
The gross surgical pathologic features of the aortic valve were reviewed in 213 patients who had had clinically combined aortic stenosis and insufficiency and aortic valve replacement at our institution during the years 1965, 1970, 1975, and 1980. The three most common causes were postinflammatory disease (69%) and calcification of congenitally bicuspid (19%) and unicommissural (6%) aortic valves. Other causes included infective endocarditis (2%) and congenitally quadricuspid or malformed tricuspid aortic valves (1% each); the cause was indeterminate in 1%. In the postinflammatory and bicuspid states, calcification tended to be more extensive in men than in women. The relative incidence of postinflammatory disease in our study did not change appreciably from 1965 to 1980, despite the steadily decreasing incidence of acute rheumatic fever reported in western countries.
R Subramanian; L J Olson; W D Edwards
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Mayo Clinic proceedings     Volume:  60     ISSN:  0025-6196     ISO Abbreviation:  Mayo Clin. Proc.     Publication Date:  1985 Apr 
Date Detail:
Created Date:  1985-05-02     Completed Date:  1985-05-02     Revised Date:  2013-12-13    
Medline Journal Info:
Nlm Unique ID:  0405543     Medline TA:  Mayo Clin Proc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  247-54     Citation Subset:  AIM; IM    
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MeSH Terms
Aortic Valve / abnormalities,  pathology,  surgery
Aortic Valve Insufficiency / complications,  pathology*,  surgery
Aortic Valve Stenosis / complications,  pathology*,  surgery
Calcinosis / pathology
Endocarditis / pathology
Heart Valve Diseases / complications,  pathology
Middle Aged
Mitral Valve / pathology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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