| Surgical outcomes with 360-degree suture trabeculotomy in poor-prognosis primary congenital glaucoma and glaucoma associated with congenital anomalies or cataract surgery. | |
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MedLine Citation:
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PMID: 21397807 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To evaluate the outcomes of 360-degree suture trabeculotomy in childhood glaucoma with poor prognosis. METHODS: A nonrandomized, retrospective chart review was performed on pediatric patients (younger than 18 years of age) treated with a 360-degree suture trabeculotomy for glaucoma. The cases were categorized into the following groups: (1) primary congenital glaucoma with birth-onset presentation accompanied by corneal clouding noted at birth, (2) primary congenital glaucoma with onset or presentation after 1 year of age, (3) primary congenital glaucoma with previous failed goniotomy surgery, (4) infantile-onset glaucoma following congenital cataract surgery, and (5) infantile-onset glaucoma with associated ocular/systemic anomalies. RESULTS: A total of 45 eyes of 33 patients were analyzed. The mean preoperative intraocular pressure (IOP) was 34.3±6.7 mm Hg on an average of 1.5 medications. Median age at time of surgery was 7 months. Mean final IOP (median last follow-up or failure, 12 months) was 22.2±7.1 mm Hg on an average of 1.5 medications. The probability of success according to time after surgery was 87% at 6 months, 63% at 1 year, and 58% at 2 years. Kaplan-Meier analysis of Groups 1-4 versus Group 5 failed to demonstrate a statistically significant difference (p=0.13). Of 5 eyes with port wine mark-related glaucoma, 2 had a large (>50%), persistent postoperative hyphema, and concurrent vitreous hemorrhage. CONCLUSIONS: Children with a range of ocular pathologies can be successfully treated with 360-degree suture trabeculotomy. Further evaluation of this surgical technique in primary congenital glaucoma and open-angle glaucoma following congenital cataract surgery is warranted. |
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Authors:
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Allen D Beck; Michael J Lynn; James Crandall; Omar Mobin-Uddin |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus Volume: 15 ISSN: 1528-3933 ISO Abbreviation: J AAPOS Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-03-14 Completed Date: 2011-06-10 Revised Date: 2013-05-24 |
Medline Journal Info:
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Nlm Unique ID: 9710011 Medline TA: J AAPOS Country: United States |
Other Details:
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Languages: eng Pagination: 54-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved. |
Affiliation:
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Department of Ophthalmology, Emory University Medical Center, Atlanta, Georgia 30322, USA. abeck@emory.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antihypertensive Agents
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administration & dosage Cataract Extraction / adverse effects* Eye Abnormalities / complications* Follow-Up Studies Glaucoma / etiology, surgery* Humans Hydrophthalmos / etiology, surgery* Infant Intraocular Pressure / physiology Prognosis Retrospective Studies Suture Techniques* Trabeculectomy / methods* Visual Acuity / physiology |
| Grant Support | |
ID/Acronym/Agency:
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P30 EY006360-24/EY/NEI NIH HHS; P30 EYO6360//PHS HHS |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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