Document Detail

Surgical outcomes with 360-degree suture trabeculotomy in poor-prognosis primary congenital glaucoma and glaucoma associated with congenital anomalies or cataract surgery.
MedLine Citation:
PMID:  21397807     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To evaluate the outcomes of 360-degree suture trabeculotomy in childhood glaucoma with poor prognosis.
METHODS: A nonrandomized, retrospective chart review was performed on pediatric patients (younger than 18 years of age) treated with a 360-degree suture trabeculotomy for glaucoma. The cases were categorized into the following groups: (1) primary congenital glaucoma with birth-onset presentation accompanied by corneal clouding noted at birth, (2) primary congenital glaucoma with onset or presentation after 1 year of age, (3) primary congenital glaucoma with previous failed goniotomy surgery, (4) infantile-onset glaucoma following congenital cataract surgery, and (5) infantile-onset glaucoma with associated ocular/systemic anomalies.
RESULTS: A total of 45 eyes of 33 patients were analyzed. The mean preoperative intraocular pressure (IOP) was 34.3±6.7 mm Hg on an average of 1.5 medications. Median age at time of surgery was 7 months. Mean final IOP (median last follow-up or failure, 12 months) was 22.2±7.1 mm Hg on an average of 1.5 medications. The probability of success according to time after surgery was 87% at 6 months, 63% at 1 year, and 58% at 2 years. Kaplan-Meier analysis of Groups 1-4 versus Group 5 failed to demonstrate a statistically significant difference (p=0.13). Of 5 eyes with port wine mark-related glaucoma, 2 had a large (>50%), persistent postoperative hyphema, and concurrent vitreous hemorrhage.
CONCLUSIONS: Children with a range of ocular pathologies can be successfully treated with 360-degree suture trabeculotomy. Further evaluation of this surgical technique in primary congenital glaucoma and open-angle glaucoma following congenital cataract surgery is warranted.
Allen D Beck; Michael J Lynn; James Crandall; Omar Mobin-Uddin
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus     Volume:  15     ISSN:  1528-3933     ISO Abbreviation:  J AAPOS     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-03-14     Completed Date:  2011-06-10     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  9710011     Medline TA:  J AAPOS     Country:  United States    
Other Details:
Languages:  eng     Pagination:  54-8     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 American Association for Pediatric Ophthalmology and Strabismus. Published by Mosby, Inc. All rights reserved.
Department of Ophthalmology, Emory University Medical Center, Atlanta, Georgia 30322, USA.
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MeSH Terms
Antihypertensive Agents / administration & dosage
Cataract Extraction / adverse effects*
Eye Abnormalities / complications*
Follow-Up Studies
Glaucoma / etiology,  surgery*
Hydrophthalmos / etiology,  surgery*
Intraocular Pressure / physiology
Retrospective Studies
Suture Techniques*
Trabeculectomy / methods*
Visual Acuity / physiology
Grant Support
P30 EY006360-24/EY/NEI NIH HHS; P30 EYO6360//PHS HHS
Reg. No./Substance:
0/Antihypertensive Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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