Document Detail

Surgical morbidity associated with radical trachelectomy and radical hysterectomy.
MedLine Citation:
PMID:  16343604     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: To examine intra-operative, short and longer term morbidity associated with Radical Trachelectomy (RT) within our cohort of patients, compared with conventional Radical Hysterectomy (RH). METHODS: A retrospective case note review comprising 29 RT and 50 RH patients. Patients who required adjuvant treatment were excluded. Operative data, short-term and long-term complications were recorded. Long-term problems were included only if they had been of persistent nature. RESULTS: The median age and follow up period for the RH group were 40 years and 60 months and for RT group 30.5 years and 25 months. There were significant differences between RH and RT groups in median operative time (260 versus 187 min), blood loss (1000 versus 400 ml), transfusion requirement (75% versus 12%), analgesic requirement (8 versus 3.5 days) and hospital stay (11 versus 6 days). Bladder hypotonia requiring prolonged catheterisation was more frequent in RH group (P = 0.004). There was no apparent difference in psychosexual problems between the two groups (17 versus 16%). Complications of deep dyspareunia (P = 0.009), excessive vaginal discharge (P = 0.01), and upper thigh parasthesia (P = 0.05) were noted to be significantly higher in the RT group. Specific problems encountered in the RT group included; dysmenorrhea (24%), irregular menstruation (17%), recurrent candidiasis (14%), cervical suture problems (14%), isthmic stenosis (10%) and prolonged amenorrhea (7%). CONCLUSION: RT is associated with less operative and short-term morbidity compared with conventional RH. In addition to specific complications associated with RT, in our experience, there are long-term morbidities that are not as commonly observed in RH.
F Alexander-Sefre; N Chee; C Spencer; U Menon; J H Shepherd
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Publication Detail:
Type:  Journal Article     Date:  2005-12-15
Journal Detail:
Title:  Gynecologic oncology     Volume:  101     ISSN:  0090-8258     ISO Abbreviation:  Gynecol. Oncol.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-05-25     Completed Date:  2006-06-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0365304     Medline TA:  Gynecol Oncol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  450-4     Citation Subset:  IM    
Department of Gynaecological Oncology, St. Bartholomew's Hospital, North East London Gynaecological Cancer Centre, London, UK. F.Alexander.Sefre@NorthGlasgow.Scot.NHS.UK
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MeSH Terms
Follow-Up Studies
Genital Neoplasms, Female / surgery*
Gynecologic Surgical Procedures / adverse effects*
Hysterectomy / adverse effects*
Intraoperative Complications
Middle Aged

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