Document Detail


Surgical management of portal hypertension in Felty's syndrome: A case report and literature review.
MedLine Citation:
PMID:  19231014     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND/AIMS: Bleeding esophageal varices are a common complication of portal hypertension in patients with underlying liver disease. Often patients with hepatic cirrhosis have hypersplenism with thrombocytopenia and leukopenia. Felty's syndrome is a disorder where patients with rheumatoid arthritis develop splenomegaly, neutropenia, and on rare occasions, portal hypertension without underlying cirrhosis. METHODS: We present a case of a patient with portal hypertension secondary to Felty's syndrome and discuss the importance of recognizing this condition since the treatment of choice is surgical management with splenectomy. A review of the literature and underlying liver histologic features are discussed. RESULTS: Medical and surgical management of patients with Felty's syndrome is different from those with portal hypertension due to cirrhosis. CONCLUSION: Splenectomy is the treatment of choice for complications of portal hypertension in patients with Felty's Syndrome.
Authors:
Heather Stock; Zakiyah Kadry; Jill P Smith
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-02-12
Journal Detail:
Title:  Journal of hepatology     Volume:  50     ISSN:  0168-8278     ISO Abbreviation:  J. Hepatol.     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-03-16     Completed Date:  2009-07-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8503886     Medline TA:  J Hepatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  831-5     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Harrisburg Hospital, Harriburg, PA, USA.
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MeSH Terms
Descriptor/Qualifier:
Esophageal and Gastric Varices / surgery
Felty's Syndrome / complications*
Hematemesis / etiology
Humans
Hypertension, Portal / complications,  surgery*
Male
Middle Aged
Pulmonary Disease, Chronic Obstructive / complications
Splenectomy
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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