Document Detail


Surgical management of lipoblastoma.
MedLine Citation:
PMID:  16769336     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND/PURPOSE: Lipoblastoma/lipoblastomatosis, a rare benign pediatric tumor composed of embryonic fat, most often presents as a rapidly growing mass in children younger than 3 years. This benign tumor locally recurs up to 25% of the time. This retrospective review was done to emphasize problems with diagnosis, management, and the approach to follow-up care. METHODS: Sixteen cases of pathologically proven lipoblastoma presenting to a single institution over a 16-year period (1988-2004) were reviewed retrospectively for clinical features and outcome. RESULTS: There were 11 males and 5 females ranging in age from 18 days to 12.75 years. Preoperative diagnoses were accurate in only 3 cases. Two lesions recurred locally over a period of 10 months and 5 years. One lesion presented with local infiltration. Six lesions were right-sided, 5 were left-sided, and 5 were midline. CONCLUSIONS: It is important to consider lipoblastoma in the diagnosis of a rapidly enlarging fatty mass in children. Complete resection is the only definitive treatment and should not be delayed when impingement on surrounding structures is imminent. There is a tendency for these lesions to recur despite presumed complete excision. Therefore, follow-up for a minimum of 5 years is recommended.
Authors:
Marcene R McVay; Jennifer E Keller; Charles W Wagner; Richard J Jackson; Samuel D Smith
Related Documents :
7244726 - "incidental"adrenal cyst: a correctable lesion possibly associated with hypertension.
10949426 - Adrenal masses in the newborn.
8798026 - Macronodular congenital adrenal hyperplasia in an adult with female pseudohermaphroditism.
17249466 - Retroperitoneal foregut duplication cyst presenting as an adrenal mass.
25332616 - Relapsed hodgkin's lymphoma presenting with isolated ulcerative lesion on base of tongue.
25462056 - Post-splenectomy splenosis presenting as hepatocellular carcinoma in the left lateral s...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  41     ISSN:  1531-5037     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-06-13     Completed Date:  2006-10-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1067-71     Citation Subset:  IM    
Affiliation:
Department of Surgery, University of Arkansas for Medical Sciences, Little Rock, AR 72202-3591, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Child
Child, Preschool
Diagnosis, Differential
Female
Humans
Infant
Infant, Newborn
Lipoma / diagnosis,  genetics,  pathology,  surgery*
Magnetic Resonance Imaging
Male
Neoplasm Invasiveness
Neoplasm Recurrence, Local

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The expression of HSP70 and HSP90alpha in children with Wilms tumor.
Next Document:  Differential response of neuroblastoma cells to TRAIL is independent of PI3K/AKT.