| Surgical management of life-threatening epistaxis in Osler-Weber-Rendu disease. | |
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MedLine Citation:
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PMID: 7486747 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hereditary hemorrhagic telangiectasia is a systemic disorder of blood vessels. It often leads to severe epistaxis that is refractory to conventional therapy. Three patients with severe epistaxis caused by hereditary hemorrhagic telangiectasia unresponsive to laser coagulation and to septal dermoplasty and requiring multiple transfusions underwent extirpation of nasal mucosa through a rhinotomy approach, with a median forehead flap and split-thickness skin graft coverage of the mucosal defects over the floor and lateral walls of the nose. All patients had reduced frequency and severity of bleeding without any need for transfusions during follow-up periods of 6 months, 3 years, and 5 years, respectively. Forehead flaps resulted in minimal morbidity. Partial nasal obstruction and a forehead scar were the main complaints. Surgical technique, complications, and alternative therapy are discussed. |
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Authors:
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E E Rebeiz; D J Bryan; R J Ehrlichman; S M Shapshay |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Annals of plastic surgery Volume: 35 ISSN: 0148-7043 ISO Abbreviation: Ann Plast Surg Publication Date: 1995 Aug |
Date Detail:
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Created Date: 1995-11-30 Completed Date: 1995-11-30 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 7805336 Medline TA: Ann Plast Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 208-13 Citation Subset: IM |
Affiliation:
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Department of Otolaryngology, Head and Neck Surgery, Lahey Clinic, Burlington, MA, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Epistaxis
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etiology,
surgery* Humans Male Methods Middle Aged Surgical Flaps* Telangiectasia, Hereditary Hemorrhagic / complications* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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