| Surgical management of MEN-1 and -2: state of the art. | |
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MedLine Citation:
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PMID: 19836484 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Multiple endocrine neoplasia syndrome type 1 (MEN-1) consists of endocrine tumors of the parathyroid, the endocrine pancreas-duodenum, and the pituitary. Surveillance and screening for the endocrinopathies is recommended in gene carriers. Surgery for MEN-1-related hyperparathyroidism is generally performed as radical subtotal parathyroidectomy, because less surgery is likely to result in persistent or recurrent disease. Multiple endocrine neoplasia syndrome type 2 (MEN-2) consists of medullary thyroid carcinoma, pheochromocytoma, and hyperparathyroidism. Prophylactic thyroidectomy based on DNA testing in the MEN-2 syndrome is considered one of the greater achievements in cancer treatment, because it may be performed before thyroid carcinoma development and provides cure for the patient. |
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Authors:
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Göran Akerström; Peter Stålberg |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The Surgical clinics of North America Volume: 89 ISSN: 1558-3171 ISO Abbreviation: Surg. Clin. North Am. Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-10-19 Completed Date: 2009-12-03 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0074243 Medline TA: Surg Clin North Am Country: United States |
Other Details:
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Languages: eng Pagination: 1047-68 Citation Subset: AIM; IM |
Affiliation:
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Department of Surgery, University Hospital, Uppsala, 751 85 Sweden. goran.akerstrom@surgsci.uu.se |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenal Gland Neoplasms
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blood,
genetics,
surgery Carcinoma, Medullary / blood, genetics, surgery Endocrine Surgical Procedures / methods* Genetic Testing Genotype Humans Hyperparathyroidism / blood, genetics, surgery Multiple Endocrine Neoplasia Type 1 / blood, genetics, surgery* Multiple Endocrine Neoplasia Type 2a / blood, genetics, surgery* Parathyroidectomy Pheochromocytoma / blood, genetics, surgery |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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