Document Detail


Surgical induction of chorioretinal venous anastomosis in ischaemic central retinal vein occlusion: a non-randomised controlled clinical trial.
MedLine Citation:
PMID:  15615749     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
AIM: To evaluate the safety and efficacy of surgical induction of chorioretinal venous anastomosis in the management of ischaemic central retinal vein occlusion (CRVO).
METHODS: In a comparative clinical trial, 28 patients with ischaemic CRVO were included, of whom 18 who declined surgery were considered as controls. The 10 surgical cases underwent standard vitrectomy with incisions into the choroids adjacent to the partially cut major retinal veins. Mersilene suture insertion was done to induce chorioretinal venous shunt. Mild endolaser was applied. Patients were followed up for 6-18 (mean 10) months.
RESULTS: Clinical success in shunt development was 90%. Surgical cases had a significantly better visual acuity improvement compared with controls (mean difference: 1.5 logMAR, p = 0.001) with 80% of them showing improvement (compared with 28% of the controls, p = 0.016). Neovascularisation developed in 39% of the control group compared with 0% of the surgical cases (p = 0.03). In multivariate analysis, surgery remained the sole significant predictor of visual improvement. There were three re-operations for vitreous cavity haemorrhage, cataract, and retinal detachment.
CONCLUSIONS: Surgical induction of chorioretinal venous anastomosis may result in visual acuity improvement and prevent neovascularisation in ischaemic CRVO. Randomised studies are needed to compare the current study modality with the natural course of CRVO and emerging procedures, such as optic neurotomy, in the management of ischaemic CRVO.
Authors:
A Mirshahi; R Roohipoor; A Lashay; S F Mohammadi; M R Mansouri
Related Documents :
3447849 - Analysis of the dosage controversy in recess-resect and faden surgery with the robinson...
16857499 - Role of flap thickness in laser in situ keratomileusis enhancement for refractive under...
17641709 - Severe retinal injuries from paintball projectiles.
7817029 - External argon laser choroidotomy versus needle drainage technique in primary scleral b...
18356929 - Postoperative endophthalmitis: optimal management and the role and timing of vitrectomy...
19861749 - Combination 20 and 23-gauge transconjunctival vitrectomy: a new approach.
24103859 - Is the surgeon still the main prognosis factor?
20552369 - Laparoscopic versus open appendectomy in men: a prospective randomized trial.
24661639 - Robotic nephroureterectomy: a simplified approach requiring no patient repositioning or...
Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  The British journal of ophthalmology     Volume:  89     ISSN:  0007-1161     ISO Abbreviation:  Br J Ophthalmol     Publication Date:  2005 Jan 
Date Detail:
Created Date:  2004-12-23     Completed Date:  2005-01-18     Revised Date:  2013-06-09    
Medline Journal Info:
Nlm Unique ID:  0421041     Medline TA:  Br J Ophthalmol     Country:  England    
Other Details:
Languages:  eng     Pagination:  64-9     Citation Subset:  IM    
Affiliation:
Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, PO Box 14155-7146, Tehran, Iran.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Aged, 80 and over
Anastomosis, Surgical / methods
Choroid / surgery*
Choroidal Neovascularization / etiology,  prevention & control
Female
Fluorescein Angiography / methods
Humans
Male
Middle Aged
Postoperative Complications / etiology,  prevention & control
Retina / surgery*
Retinal Neovascularization / etiology,  prevention & control
Retinal Vein Occlusion / complications,  physiopathology,  surgery*
Treatment Outcome
Visual Acuity / physiology
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Increased plasma endothelin-1 levels in patients with progressive open angle glaucoma.
Next Document:  Acute zonal occult outer retinopathy: towards a set of diagnostic criteria.