Document Detail


Surgical distance to the sphenoid ostium: a comparison of healthy patients and patients with cystic fibrosis.
MedLine Citation:
PMID:  20479379     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To establish and compare the distance and angle from the limen nasi to the sphenoid ostium in pediatric patients with normal sinonasal anatomy vs pediatric patients with cystic fibrosis (CF). DESIGN: Retrospective review of computed tomographic images. SETTING: Tertiary university-based medical center. PARTICIPANTS: Patients (newborn to age 20 years) with normal sinonasal anatomy (n = 117) or CF (n = 15). MAIN OUTCOME MEASURES: We used a fourth-degree polynomial to curve-fit the distance to the sphenoid ostium vs age for patients with normal sinonasal anatomy, producing a coefficient of determination (R(2)) of 82%. With this regression curve, we produced a normative distance equation and a normative distance graph using age to predict the distance (95% confidence interval). We validated the normative distance curve fit among 30 new pediatric patients. RESULTS: No significant difference in the distance to the sphenoid ostium was found between healthy patients and patients with CF. There was no correlation between age and angle in either patient group. The mean (SD) angle was statistically different between healthy patients (37.5 degrees [7.5 degrees]) and patients with CF (41.4 degrees [7.4 degrees]). CONCLUSIONS: Using a normative distance graph and the mean angle, surgeons performing pediatric endoscopic sinus surgery can predict the distance to the sphenoid ostium for healthy patients and for patients with CF. These findings may decrease complications of endoscopic sinus surgery among the pediatric population.
Authors:
Xiao Zhao; Shamir Chandarana; Murad Husein; John Rogers; Duncan L MacRae
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Publication Detail:
Type:  Comparative Study; Journal Article; Validation Studies    
Journal Detail:
Title:  Archives of otolaryngology--head & neck surgery     Volume:  136     ISSN:  1538-361X     ISO Abbreviation:  Arch. Otolaryngol. Head Neck Surg.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-18     Completed Date:  2010-06-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8603209     Medline TA:  Arch Otolaryngol Head Neck Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  475-9     Citation Subset:  AIM; IM    
Affiliation:
Schulich School of Medicine and Dentistry, The University of Western Ontario, Ontario, Canada.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Child
Child, Preschool
Cystic Fibrosis / pathology*
Endoscopy
Female
Humans
Infant
Infant, Newborn
Male
Reference Values
Regression Analysis
Retrospective Studies
Sphenoid Sinus / anatomy & histology*,  radiography,  surgery
Tomography, X-Ray Computed
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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